Encapsulation of bioactives using nature-derived hydrophobic proteins
A novel encapsulation technology using corn zein and silk proteins for hydrophobic bioactives, offering eco-friendly alternatives to micro-plastic pollution. This method employs green chemistry to enhance encapsulation efficiency and scalability via cost-effective production techniques.
Overview
This innovative technology leverages the natural hydrophobic properties of corn zein and silk proteins for encapsulating hydrophobic bioactive ingredients, offering an environmentally friendly solution to micro-plastic pollution concerns. By fine-tuning the surface chemistry and encapsulation process through green chemistry, this method achieves desired particle sizes and morphologies. It presents a scalable, cost-effective alternative for industries looking to implement sustainable encapsulation methods.
Technical specifications
Key features:
- Utilizes natural macromolecules like corn zein and silk protein for encapsulation.
- Incorporates green chemistry techniques to modify surface chemistry, enhancing encapsulation efficiency.
- Capable of producing encapsulated particles through scalable methods such as core-shell solution blowing and co-precipitation with spray-drying.
- Adaptable to various bioactive compounds by tailoring the hydrophobicity and functional groups of the proteins.
Technology readiness level
This technology is currently at Technology Readiness Level 4, indicating that it has been validated in a laboratory setting. Future validation will focus on assessing compatibility with specific bioactive molecules, optimizing encapsulation processes, and conducting comprehensive testing for release profiles, biodegradability, and scalability for large-scale production.
About University of Waterloo
University of Waterloo is a public research university in Ontario, Canada, known for an entrepreneurial, STEM‑driven culture. A globally recognized co‑op program places students with employers year‑round, creating direct talent pipelines and de‑risked pathways into sponsored research and contract development. An adjacent research and technology park hosts corporate R&D alongside faculty labs, and the campus sits within the Toronto–Waterloo innovation corridor for ready access to partners, investors, and scale‑up resources. Research is supported by competitive federal funding from Canada’s Tri‑Council agencies (NSERC, CIHR, SSHRC) and international programs. A creator‑owned IP policy and a dedicated tech transfer office enable flexible agreements, licensing, and spinouts.
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