Encapsulation technology for improved micronutrient delivery and bioavailability

Technology
In development
University

Fraunhofer IMM's encapsulation technology enhances micronutrient delivery through polymer-based capsules with controlled release, improving bioavailability. Suitable for vitamins, enzymes, and minerals, it offers applications in food, pharmaceuticals, and nutraceuticals.

Overview

Fraunhofer IMM presents an innovative encapsulation technology designed to improve the delivery and bioavailability of micronutrients. By utilizing polymer-based particles, hydrogels, and capsules, this technology enables the controlled and programmed release of active agents such as vitamins, enzymes, and minerals. The encapsulation process addresses challenges like poor solubility and inefficient gastrointestinal delivery, optimizing the efficacy and benefits for end users. The technology supports various industrial applications, including food, pharmaceuticals, and nutraceuticals.

Technical specifications

Key features:

  • Versatile Encapsulation: Utilizes biomaterials like polysaccharides, lipids, proteins, and natural waxes to create capsules ranging from 50 nm to several mm in diameter.
  • Advanced Methods: Employs nanoemulsification, solubilization, coacervation, and nanoprecipitation to encapsulate active agents.
  • Controlled Release: Capsules exhibit controlled and delayed release profiles, validated through in vitro tests.
  • Scalable Production: Initial batch processes can be scaled up using continuous flow setups for controlled and reproducible encapsulation.
Technology readiness level

Currently at TRL 4, this technology has been validated in laboratory settings with plans for further development through process optimization and scaling up. Future steps include material selection, encapsulation parameter definition, and process optimization to enhance performance and applicability.


About Fraunhofer Institute

Fraunhofer is a large, multi-site applied research organization based in Germany, operating a nationwide network of institutes and research units with a strong industry-facing mission. Its contract-research model aligns work to real manufacturing and deployment needs, with pilot lines, test labs, and demonstration facilities for validation and scale-up. Many institutes are integrated with nearby universities and regional industry clusters, enabling joint appointments, shared infrastructure, and fast talent pipelines. Research is supported by competitive European programs alongside German federal and state funding, complemented by extensive contract revenue from private-sector collaborations. A dedicated technology transfer function manages IP, licensing, and startup formation.

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