Engineered yeast strains for improved bioethanol production stability and efficiency

Overview

Ex Seed has developed a proprietary genetic engineering technology that modifies industrial yeast strains used in bioethanol production. The engineered yeast eliminates flocculation and foam formation, which are common issues that hinder the efficiency of bioethanol production. This advancement significantly enhances the stability and robustness of the process, particularly when using sugar cane juice or molasses as feedstock. The solution is applicable to both standard industrial strains and personalized yeast strains, offering flexibility and immediate applicability in the industry.

Technical specifications

Key features:

• Elimination of flocculation and foam through the deletion of sugar-binding domains in FLO genes by cisgenic engineering.
• Enhanced process stability by reducing bacterial contamination, as yeast flocs that trap bacteria are no longer formed.
• Compatibility with Brazilian industrial yeast strains (PE2, CAT1, BG1, SA1) and personalized yeast strains.
• Minimal risk of side effects on other industrially-important properties of the yeast.

Technology readiness level

This technology is at TRL 5, indicating that it has been validated in a relevant environment. Future validation steps include whole-genome sequencing and further genetic modifications, with potential GMO deregulation in progress. Licensing opportunities are immediately available for modified strains.