Enhanced micronutrient delivery via buccal and sublingual films
A novel system for delivering vitamins and minerals through buccal and sublingual films, bypassing the GI tract for improved absorption and bioavailability. This technology uses biocompatible polymers to create films that dissolve in the mouth, providing precise dosing and stability.
Overview
The innovative buccal and sublingual film technology offers a groundbreaking approach to delivering micronutrients directly into the bloodstream, bypassing the gastrointestinal tract. This method enhances bioavailability by avoiding first-pass metabolism and acidic degradation, which are typical drawbacks of traditional oral supplements. The films are designed to dissolve swiftly in the oral cavity, ensuring that vitamins and minerals like magnesium, iron, and vitamin D are absorbed efficiently through the highly vascularized oral mucosa. This delivery system is ideal for those requiring rapid nutrient uptake and precise dosing.
Technical specifications
The films are composed of biocompatible polymers such as hydroxypropyl methylcellulose (HPMC), ensuring they are safe for oral administration. Key features include:
- Rapid dissolution: The films dissolve in 1-3 minutes, allowing for quick nutrient release.
- Tailored composition: The polymer matrix can be adjusted to control the dissolution rate and nutrient release.
- Alternative formats: Jellies and gummies are also available, providing a user-friendly option for children and the elderly, without compromising on stability and effectiveness.
Technology readiness level
Currently at TRL 3, this technology is in the developmental phase. Initial prototypes have been created, and stability testing is underway. Future phases involve in vitro dissolution testing, cytotoxicity assessments, and a pilot study comparing bioavailability with traditional tablets, paving the way for regulatory approval and commercialization.
About 3DFying
3DFying is a company that offers specialized 3D design, prototyping, and printing services tailored to the pharmaceutical, nutraceutical, medical, and dental industries. They provide customized 3D printing solutions, including the development of specialized printers and research into personalized medication printing, such as the production of pills for clinical and exploratory trials. The company also hosts hands-on training programs and workshops designed to integrate 3D printing technology into various scientific and medical professional domains.
These services address the needs of researchers and clinicians by offering customized hardware and technical support to facilitate innovation in fields like drug delivery and patient-specific treatments. By providing both the equipment and the methodological expertise, 3DFying supports partners in navigating the technical challenges of 3D manufacturing in highly regulated sectors. Their work facilitates the development of personalized medicinal dosage forms and specialized orthodontic or medical components, contributing to advancements in digital healthcare and pharmaceutical research.
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