Gene editing for increased trichome density in solanaceae
A gene editing technology enhancing trichome density in Solanaceae plants, improving disease and pest resistance through silencing specific genes. Applicable to crops like tomatoes and peppers, with potential expansion to cucurbits.
Overview
This innovative gene editing technology focuses on enhancing the trichome density in Solanaceae plants, such as tomatoes and peppers, to improve their resistance to diseases and pests. By silencing specific genes that control glandular trichome formation, this solution not only increases trichome density but also boosts the production of protective secondary metabolites associated with these structures. This enhancement provides a robust defense mechanism against various agricultural challenges, offering significant benefits for crop yield and sustainability.
Technical specifications
Key features:
- Utilizes targeted gene silencing to increase glandular trichome density in Solanaceae plants.
- Enhances production of secondary metabolites, which are crucial for pest and disease resistance.
- Demonstrated efficacy in target crops with potential adaptability to cucurbits, expanding its application range.
- Correlation between the number of silenced genes and the level of trichome and metabolite increase, allowing for scalable implementation.
Technology readiness level
The technology is currently at TRL 5, indicating that it has been validated in a laboratory environment. Future validation steps will involve making edits in suggested target plants to further assess and refine the approach for broader agricultural use.
About University of Virginia
The University of Virginia is a comprehensive public research university with broad academic programs and a robust research enterprise. Integration with UVA Health enables clinical translation, large-scale trials, and data-driven care in an academic medical setting. A university-operated discovery park, North Fork—A UVA Discovery Park, co-locates companies with faculty and government partners, while participation in the Commonwealth Center for Advanced Manufacturing gives access to production-scale testbeds and joint industry projects. Research is supported by competitive federal funding, including NIH, NSF, DOE, and DoD. The Licensing & Ventures Group manages IP, licensing, and startup formation to speed commercialization.
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