High-throughput ft-raman screening for skin and hair follicle health
A portable FT-Raman device for non-invasive monitoring of skin and hair follicle health using low-power 830 nm laser. This technology captures key biomarkers through depth-resolved spectra, enabling early detection of biochemical changes.
Overview
The high-throughput FT-Raman screening technology provides a non-invasive solution to monitor skin and hair follicle health. Utilizing a portable device with a low-power 830 nm laser, this technology enables direct, in situ analysis of the subject's skin and hair follicles. By capturing depth-resolved spectra, it evaluates crucial biomarkers such as keratin disulfide bonds, ceramide barrier functions, collagen structure, carotenoid antioxidant levels, and natural moisturizing factor. This approach allows for early detection of biochemical changes before visible symptoms appear, offering a proactive tool for health monitoring.
Technical specifications
- Portable FT-Raman Device: Operates with a low-power 830 nm laser, minimizing fluorescence and allowing deep penetration to follicle structures.
- Miniature Michelson Interferometer and Avalanche Diode: Ensures precision and efficiency in data collection.
- Direct Contact or Tethered Fiber-Optic Probe: Provides flexibility in application methods.
- Standardized 12-Point Scalp Mapping: Ensures longitudinal reproducibility and accurate monitoring over time.
- Data Synchronization: Spectra are synced to a tablet or PC for comprehensive data processing and analysis.
Technology readiness level
This technology is currently at TRL 2, indicating that the concept and application have been formulated but require further validation and testing in practical scenarios. Future validation plans include robust baseline establishment and longitudinal monitoring to quantify formulation effects on skin and hair health.
About SKM Instruments
SKM Instruments designs and manufactures custom, compact FT-Raman spectroscopy systems that provide laboratory-grade analytical performance in a ruggedized form factor. Their technology leverages laser-locked calibration and high-throughput optics to deliver consistent, high-precision Raman spectra. By applying principles commonly found in FTIR—such as the Connes’ advantage—these instruments offer enhanced stability and sensitivity for demanding analytical environments. This approach is specifically engineered to improve the performance of chemometric models and spectral library development, providing a reliable alternative to traditional dispersive Raman systems in applications where calibration stability and long-term cost efficiency are prioritized. Their systems are tailored for specialized industrial and research applications, particularly where high laser power density or complex environmental factors present challenges. By offering a robust, application-focused design, SKM enables users to deploy sophisticated spectroscopic analysis outside of controlled laboratory settings while maintaining high data accuracy and reduced calibration maintenance.
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