High throughput tissue healing analysis platform

Technology
In development
University

A cutting-edge platform for high throughput tissue healing analysis, featuring engineered tissue generation, automated live imaging, and advanced computational analysis to optimize wound healing research. Ideal for sponsored research collaborations.

Overview

Our high throughput tissue healing analysis platform offers a revolutionary approach to understanding and optimizing wound healing. Leveraging advanced tissue engineering, live imaging, and proprietary analysis methods, this platform goes beyond traditional assays to provide deep insights into complex healing dynamics. By focusing on cellular crowd behavior, mechanical changes, and regenerative processes, we provide a comprehensive understanding of the healing process that can inform the development of more effective therapeutic strategies.

Technical specifications
  • Tissue Generation: Custom-engineered tissues using advanced stencils and robotic platforms, allowing for precise control over wound and tissue geometry.
  • Live Imaging: High-frame rate, automated imaging using phase contrast and fluorescence techniques, capturing detailed cellular dynamics over time.
  • Advanced Analysis: Innovative methods for analyzing cellular crowd dynamics, mechanical forces, and regenerative elements, offering insights beyond traditional gap closure metrics.
  • Quantitative Tools: Spatial dynamics, proliferation patterns, mechanical force measurement, and cell coordination indices for comprehensive data analysis.
Technology readiness level

Currently at Technology Readiness Level 6, our platform has been demonstrated in relevant environments, and we are seeking sponsored research partnerships to further validate and optimize our methods in collaboration with industry partners.


About Princeton University

Princeton University is a private, research-intensive university in Princeton, New Jersey, known for a tightly integrated campus and a globally connected research enterprise. Industry partners engage through a dedicated corporate relations team that brokers sponsored research, consortia, and talent pipelines. Co-located assets include shared user facilities for advanced imaging and nanofabrication, a university-managed U.S. Department of Energy national lab, and a research park that hosts corporate collaborators. Research is supported by competitive federal funding from agencies such as NSF, NIH, DOE, DoD, and NASA. A technology transfer office provides IP strategy, licensing, and startup support, complemented by an affiliated incubator and mentor network.

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