I-optimal design of experiments for accelerated development of compostable bio-based products
Expert consulting in I-optimal design of experiments (DoE) using JMP statistical software to accelerate the development and optimization of compostable products from bio-based materials. Combines advanced statistical design with deep expertise in polymer processing techniques including extrusion blow molding, thermoforming, injection-stretch blow molding, resin transfer molding, and additive manufacturing.
Overview
This offering combines I-optimal design of experiments (DoE) methodology with JMP statistical software to reduce the development time and cost of compostable products sourced from bio-based materials. Response surface designs are a proven industrial strategy for establishing relationships between product responses and experimental factors, enabling efficient process and product optimization. The approach is particularly valuable for manufacturers seeking to develop sustainable packaging, medical devices, or tissue engineering scaffolds using bio-based feedstocks such as thermoplastic cellulose, thermoplastic starch, and nisin.
Technical specifications
Core capabilities:
- I-optimal design of experiments using JMP statistical software for efficient experimental planning and analysis
- Formulation development and processing technique selection for bio-based and compostable materials
- Rheological characterization using twin-bore capillary rheometry
- Extrudate swell measurements via single-axis laser die swell apparatus
- Permeability analysis and mechanical testing
- Foaming capability assessment
- Thermal analysis including DSC, DMA, and fluorescence-based glass transition temperature probing
- Polymer processing across extrusion blow molding, thermoforming, injection-stretch blow molding, resin transfer molding, and additive manufacturing
Validated applications:
- 3D porous scaffold design for bone tissue engineering (NIH-funded)
- Food packaging composite development
- Industrial process optimization and medical device development
Technology readiness level
The underlying methodology is validated through an NIH-funded study on experimental and computational design of porous biomaterials, along with two academic projects on food packaging composites. The principal investigator's track record includes over 20 peer-reviewed publications, including joint studies with resin suppliers and fuel tank manufacturers. On-site rheological, thermal, mechanical, and processing characterization capabilities are available to support client engagements. The approach is ready for immediate application to new compostable product development projects.
About Miami University, Ohio
Miami University is a comprehensive public research university in Oxford, Ohio, known for a strong undergraduate focus alongside applied, collaborative research. Industry engagement centers on co-ops and internships, industry-sponsored capstone design, and open maker and prototyping spaces that support rapid iteration with faculty and student teams. Proximity to Cincinnati and Dayton puts partners near Fortune 500 headquarters, advanced manufacturing suppliers, and a dense logistics network, enabling frequent site visits and efficient scale-up. Research is supported by competitive federal and state funding, including awards from the National Science Foundation and the National Institutes of Health. A dedicated technology transfer office supports IP, licensing, and startup formation, linking companies to regional commercialization resources.
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