Innovative methodologies for discovering cryptic natural products from microbes
Explore advanced techniques for revealing hidden natural products in microbes, utilizing a novel approach to identify and characterize over 150 new metabolites. Ideal for industries seeking unique bioactive compounds from microbial sources.
Overview
Our innovative methodologies revolutionize the discovery of cryptic natural products from microbes, which are typically inaccessible through conventional methods. By leveraging our advanced techniques, we have successfully characterized over 150 novel compounds that remain hidden under standard investigation. This approach has immense potential for industries aiming to uncover unique bioactive compounds from microbial sources, offering new avenues for drug discovery, agricultural enhancements, and more.
Technical specifications
Key features:
- Utilization of advanced genomic and metabolomic mapping to identify cryptic metabolites
- Development of a 3D metabolome map for comprehensive natural product identification
- Application of HiTES technology to enhance metabolite yields and facilitate isolation of target compounds
- Expertise in structural characterization and functional analysis of novel metabolites
Technology readiness level
Our methodologies have reached a Technology Readiness Level (TRL) of 5, indicating that they have been validated in relevant environments and are ready for further development and commercial applications.
About Princeton University
Princeton University is a private, research-intensive university in Princeton, New Jersey, known for a tightly integrated campus and a globally connected research enterprise. Industry partners engage through a dedicated corporate relations team that brokers sponsored research, consortia, and talent pipelines. Co-located assets include shared user facilities for advanced imaging and nanofabrication, a university-managed U.S. Department of Energy national lab, and a research park that hosts corporate collaborators. Research is supported by competitive federal funding from agencies such as NSF, NIH, DOE, DoD, and NASA. A technology transfer office provides IP strategy, licensing, and startup support, complemented by an affiliated incubator and mentor network.
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