Kinetic delay of psyllium gelation using low-hlb edible surfactants
This innovative solution employs interfacial engineering to delay psyllium hydration, creating a temporary barrier that enhances drinkability without compromising physiological efficacy. Utilizing low-HLB de-oiled sunflower lecithin, the technology maintains the integrity of psyllium fiber while ensuring compliance with supplement GMPs.
Overview
This solution leverages interfacial engineering to delay the hydration of psyllium, a common dietary fiber, by applying a thin lipophilic layer using low-HLB de-oiled sunflower lecithin. This coating temporarily resists water absorption, allowing for a low-viscosity drinkability window of 5-10 minutes. The innovation preserves the full physiological benefits of psyllium, as the lecithin barrier is later emulsified by bile salts and pancreatic lipases in the intestine, releasing the intact fiber.
Technical specifications
- Interfacial Engineering: Employs a low-HLB (3.0–4.0) lecithin layer to delay hydration.
- Manufacturing Process: Utilizes top-spray fluidization to atomize lecithin onto psyllium particles, creating a non-hygroscopic granule.
- Rheological Profile: Targets an initial viscosity of <100 mPa.S for the first 5-10 minutes.
- Physiological Efficacy: Ensures 100% fiber release through natural emulsification in the digestive tract.
- Regulatory Compliance: Uses GRAS-certified ingredients, aligning with supplement GMPs.
Technology readiness level
The technology is currently at TRL 3, having completed initial laboratory feasibility studies and is moving towards validation in simulated gastric and intestinal environments. Plans for pilot scale trials are underway to optimize solvent recovery and coating uniformity.
About Auburn University
Auburn University is a comprehensive public land‑grant research university serving industry from its main campus in Auburn, Alabama. Companies engage through a research and technology park offering on‑site convening space and services, and via a Huntsville Research and Innovation Campus embedded in Cummings Research Park near Redstone Arsenal. A long‑standing cooperative education program and a statewide extension network link employers to student talent and field deployment across Alabama. Research is supported by competitive federal funding from agencies such as NSF, USDA, DoD, and NASA. The university’s Intellectual Property Exchange provides IP management, licensing, and commercialization support.
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