Liqui-Pellet technology for nausea-reducing multivitamins

Technology
In development
University

Liqui-Pellet technology offers a novel approach for multivitamins that reduces stomach irritation, minimizing nausea and vomiting. This method improves solubility and absorption, shortening exposure time and enhancing comfort for users.

Overview

Liqui-Pellet technology is an innovative solution designed to minimize the common side effects of nausea and vomiting associated with multivitamin consumption. By utilizing tiny pellets that disperse quickly in the stomach, this technology significantly reduces the time vitamins can irritate the stomach lining, thus diminishing the likelihood of discomfort. This approach not only improves user comfort but also enhances absorption, providing a more efficient delivery of nutrients.

Technical specifications

Key features:

  • Rapid gastric emptying: The pellets are designed to empty from the stomach as quickly as liquid, reducing irritation time.
  • Improved solubility: Insoluble active components are solubilized using non-volatile co-solvents, enhancing absorption and reducing exposure time.
  • Flexible dosage forms: Coating technology allows for delayed or controlled release, further reducing irritation.
  • Potential for reduced dosage strength: Enhanced solubility may allow for lower dosages, decreasing the risk of gastric irritation.
Technology readiness level

Currently at TRL 4, this technology has undergone lab-based validation with initial prototypes. Future steps include producing various Liqui-Pellet prototypes using different co-solvents to optimize solubility and conducting in-vitro tests for dissolution and quality control. Further optimization will involve applying coating techniques and utilizing excipients to refine the formulation.


About University of Sussex

The University of Sussex is a comprehensive public research university in Falmer, Brighton. Industry engages through the on‑campus Sussex Innovation Centre—an incubator and co‑working hub—and a dedicated Innovation and Business Partnerships team for IP, licensing, consultancy and Knowledge Transfer Partnerships. Clinical translation is enabled by the joint Brighton and Sussex Medical School with regional NHS partners, and the campus sits within a dynamic creative/digital cluster with fast links to London and Gatwick. Research is supported by UK Research and Innovation councils and Innovate UK, alongside major charities. A structured tech transfer function manages patents, spin‑outs and routes to market.

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