Lozenges with xylitol, arginine, zinc, and inulin for oral health

Technology
Conceptual
Company

An innovative oral health lozenge that combines Xylitol, Arginine, Zinc, and Inulin to improve gum health. It ensures prolonged contact with the oral cavity, supporting saliva flow, reducing harmful bacteria, and enhancing the oral microbiome.

Overview

This solution offers a novel oral health lozenge designed to improve gum health by delivering active ingredients such as Xylitol, Arginine, Zinc, and Inulin directly to the oral cavity over an extended period. The lozenge format is particularly effective because it dissolves slowly, maximizing mucosal exposure time and enabling sustained delivery to the saliva, teeth, and gingival tissues. This approach supports the growth of beneficial oral microbes while reducing bad breath, supporting saliva flow in cases of dry mouth, and aiding in enamel remineralization.

Technical specifications

Key features:

  • Contains a blend of Xylitol, Arginine, Zinc, and Inulin.
  • Slow dissolution rate ensures 5–12 minutes of contact with oral tissues.
  • Enhances saliva stimulation and increases user compliance.
  • Supports a healthier oral microbiome through prebiotic intervention.
  • Potentially reduces tooth sensitivity and plaque formation while supporting pH balance.
  • Inulin acts as a prebiotic carrier, promoting beneficial oral microbes.
Technology readiness level

This technology is currently at Technology Readiness Level 2, indicating that the concept has been formulated and initial experimentation is underway. Future validation plans include optimizing the formulation, conducting stability studies, completing safety and toxicology reviews, and defining regulatory pathways and claims strategies.


About Lozen Pharma Ltd

Lozen Pharma is a specialized manufacturer focused on the development and production of lozenges and throat pops as a novel drug delivery system (NDDS). The company utilizes confectionery formats to provide accurate dosages of natural or chemical active ingredients in palatable, convenient forms for various age groups. Their manufacturing processes allow for the customization of products, including sugar-free options and specific flavor or color profiles, designed to address diverse therapeutic healthcare needs. By operating as a dedicated partner in NDDS, they provide an alternative delivery method that is widely accepted by global regulators and consumers. The company's work enables pharmaceutical and healthcare organizations to transition therapeutic claims into user-friendly, consumer-centric delivery formats. With established international manufacturing facilities and an extensive reach across more than 40 countries, Lozen Pharma collaborates with clients to innovate and scale medicated and functional confectionery products to solve specific healthcare challenges. Their infrastructure is built to ensure quality, safety, and regulatory compliance in the production of these specialized dosage forms.

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