Micro-ring resonator sensor for lipid oxidation detection in dry animal protein
A ZIF-8-coated micro-ring resonator sensor enables selective, sensitive hexanal detection in dry animal proteins. Achieving an LOQ of ≤3.0 ppm with fast, cost-effective analysis, it offers a scalable alternative to GC-MS and LC-MS for lipid oxidation monitoring.
Overview
The proposed technology is a micro-ring resonator sensor, enhanced with a ZIF-8 coating, designed for the detection of hexanal in dry animal proteins. This innovative sensor offers a selective and sensitive method for monitoring lipid oxidation, achieving a limit of quantification (LOQ) of ≤3.0 ppm. It is designed to provide results quickly, within 60 minutes per sample, and at a low cost, under $15 per test. This solution serves as an efficient, scalable alternative to conventional methods such as Gas Chromatography-Mass Spectrometry (GC-MS) and Liquid Chromatography-Mass Spectrometry (LC-MS), which are often more complex and expensive.
Technical specifications
The sensor leverages the unique properties of ZIF-8, including its porosity, hydrophobicity, and molecular affinity, to selectively adsorb hexanal while avoiding moisture interference. The micro-ring resonator works on the principle of evanescent field interaction, where the binding of analytes causes a measurable shift in the resonant wavelength, allowing for real-time detection. The development process involves using optical simulation software to design the resonator, followed by photolithography and Reactive Ion Etching (RIE) to pattern the sensor. A ZIF-8 layer is deposited using solvothermal methods, and its structural integrity is confirmed with Scanning Electron Microscopy (SEM), X-Ray Diffraction (XRD), and FTIR.
Technology readiness level
Currently, the technology stands at a readiness level of 3, indicating that it has been experimentally validated in a laboratory setting. Future validation steps include optimizing the micro-ring design on Silicon-On-Insulator (SOI) wafers, enhancing the ZIF-8 layer application, and ensuring the sensor's scalability for industrial use. The goal is to refine the sensor to achieve the target LOQ and ensure it meets industrial standards for widespread application.
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