Microalgae-based liquid crystalline nanoparticles for enhanced antioxidant delivery
This solution leverages microalgae-based liquid crystalline nanoparticles (LCNPs) to enhance the delivery and absorption of antioxidants like carotenoids and polyphenols. Designed to combat oxidative stress, these nanoparticles promise improved solubility and bioavailability, making them a potent nutraceutical.
Overview
Microalgae-based liquid crystalline nanoparticles (LCNPs) are designed to enhance the delivery and absorption of natural antioxidants, such as carotenoids and polyphenols, which are crucial in combating oxidative stress—a key contributor to chronic diseases. The encapsulation of Chlorella extracts into LCNPs addresses the poor solubility and low bioavailability of these compounds, offering a promising nutraceutical strategy to promote human health.
Technical specifications
Key features:
- Encapsulation: Utilizes Chlorella species rich in antioxidants, encapsulated into LCNPs using techniques like high-pressure homogenization.
- Formulation Optimization: Focuses on optimizing lipid ratio and loading capacity for efficient encapsulation.
- Characterization: Involves extraction, characterization, and physicochemical assessment of nanoparticles using methods such as DLS, TEM, and SAXS/XRD.
- Sustained Release: Designed for enhanced absorption and sustained release in the gastrointestinal tract.
Technology readiness level
The technology is currently at TRL 3, having been validated through analytical studies and early-stage in vitro and in vivo evaluations. Further development and validation are planned to advance its readiness for clinical applications.
About Universiti Putra Malaysia
Universiti Putra Malaysia (UPM) is a comprehensive public research university in Serdang, Greater Kuala Lumpur, with a campus that integrates classroom, laboratory, and field-testing environments. Companies engage through co-located labs, on-campus testbeds, and university-run farms that enable prototyping and trials close to production supply chains. Health system integration and proximity to Putrajaya’s ministries and the Cyberjaya tech corridor facilitate collaboration and timely access to partners. Research is supported by competitive funding from Malaysia’s Ministry of Higher Education, the Ministry of Science, Technology and Innovation, and international sponsors. A dedicated technology transfer office manages IP, licensing, and startup support, connecting companies with faculty expertise and specialized facilities.
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