Microbial-based probiotic solution for reducing halitosis in companion animals

Technology
In development
University

A novel probiotic solution targeting oral health in pets by modulating the oral microbiome, reducing halitosis, and preventing dental plaque through safe, daily use formats such as treats and gels.

Overview

The proposed microbial-based probiotic solution addresses oral health issues in companion animals by directly targeting the oral microbiome. It aims to reduce halitosis and periodontal disease risk factors by utilizing selected lactic acid bacteria with proven antimicrobial properties. Unlike traditional mechanical or chemical oral care products, this probiotic approach offers a biological and sustainable alternative, aligning with the growing demand for natural pet health solutions.

Technical specifications

Key features:

  • Utilizes lactic acid bacteria for antimicrobial activity against oral pathogens
  • Inhibits harmful bacteria through competitive exclusion
  • Suppresses artificial plaque formation by common oral pathogens
  • Adheres effectively to oral epithelial cells
  • Designed for daily usage in pet-friendly formats such as treats, gels, and additives
Technology readiness level

The solution is currently at Technology Readiness Level 5, with ongoing experimental validation. It has been tested for efficacy through antimicrobial and competitive inhibition assays, and is undergoing safety evaluations including hemolysis testing and antibiotic resistance profiling. Further formulation and in vivo studies are planned to advance the product toward commercialization.


About Texas A&M University, College Station

Texas A&M University in College Station is a comprehensive public research university and the flagship of The Texas A&M University System, combining broad academic strengths with a strong applied‑research culture. Industry collaborates on the Texas A&M‑RELLIS campus—an integrated education, research and testing environment that supports large‑scale experimentation and proving grounds—and through the Texas A&M Transportation Institute’s facilities in Bryan‑College Station. A statewide extension network connects university expertise to companies and communities across all Texas counties, enabling rapid piloting and deployment. Research is supported by competitive federal funding from agencies such as NSF, NIH, DOE, USDA and DoD, alongside state and industry sponsorship. Texas A&M Innovation provides IP management, licensing and commercialization pathways across the system.

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