Microbial oral health platform using stabilized probiotic actives for pets

Overview

The microbial oral health platform developed by HydroBiome offers an innovative solution for managing oral health in companion animals. By leveraging stabilized probiotic strains engineered to express the bacterial hydrophilin DtpA, this platform enhances the stability and persistence of beneficial oral microbes. This approach not only reduces dental plaque, tartar buildup, and gum inflammation but also prevents the formation of biofilms, offering a natural alternative to chemical antiseptics and labor-intensive dental care routines for pets.

Technical specifications

Key features:

• Utilizes probiotic and commensal bacterial strains engineered to express DtpA for improved stability
• Enhances microbial survival under manufacturing and storage stresses such as heat and desiccation
• Competes with and disrupts plaque- and odor-causing bacteria to reduce biofilm formation
• Demonstrates potential for daily use in pet oral care products like chews, with in vitro assays confirming biofilm disruption and inhibition of harmful bacteria

Technology readiness level

The platform is currently at TRL 4, with ongoing evaluations to confirm microbial survival and activity under commercial manufacturing conditions. Preliminary safety and feasibility assessments are underway to support scalability and regulatory readiness, paving the path towards commercial development.