Microbiome feed-shift™: selective prebiotic oral ecology modulator

Technology
Conceptual
Company

Microbiome Feed-Shift™ is a selective prebiotic system designed to modulate oral ecology by supporting non-malodorous bacteria, reducing volatile sulfur compounds (VSCs) without killing bacteria. Ideal for daily use in toothpaste and lozenges.

Overview

Microbiome Feed-Shift™ is an innovative selective prebiotic substrate system developed to transform oral health care by modulating oral ecology. This technology aims to reduce volatile sulfur compounds (VSCs), which are primarily responsible for bad breath, by supporting non-malodorous commensal bacteria rather than eliminating harmful bacteria. This approach aligns with modern microbiome-friendly strategies, offering a non-aggressive solution suitable for daily oral hygiene products like toothpaste and lozenges.

Technical specifications

Core Technology:

  • Utilizes defined saccharide/polyol substrates that selectively nourish beneficial oral bacteria.
  • Operates through ecological competition to reduce VSC output, promoting a healthier oral microbiome.
  • Designed to be compatible with taste, ensuring consumer acceptance and daily usability.

Applications:

  • Daily-use oral care products such as toothpaste and lozenges.
  • Potential expansion into other oral hygiene formats that benefit from microbiome modulation.
Technology readiness level

Microbiome Feed-Shift™ is currently at Technology Readiness Level 3, indicating that active research and development are ongoing. The next steps involve ecological screening, substrate selection, prototype development, and a 28-day pilot study to further validate its efficacy.


About Sarvotham Care Ltd

Sarvotham Care Limited is an established Contract Development and Manufacturing Organization (CDMO) and Contract Manufacturing Organization (CMO) that provides comprehensive end-to-end solutions for the healthcare, personal care, and home care industries. The company manages the full product lifecycle, including formulation research and development, clinical and pre-clinical services, and commercial-scale manufacturing. Its manufacturing capabilities span various dosage forms, such as granules, powders, tablets, capsules, liquids, creams, and gels. Sarvotham emphasizes technology-driven processes, regulatory compliance, and international quality standards, supported by internal laboratories equipped for advanced microbiological and chemical analysis.

The company serves as a strategic partner to multinational corporations and large Indian firms, focusing on on-time delivery and consistent quality. By offering private label services, Sarvotham enables clients to develop and market their own branded products while leveraging the company's manufacturing expertise and R&D infrastructure. Committed to sustainability and professional integrity, Sarvotham integrates environment, health, and safety (EHS) protocols into its operations, striving to meet both local and global market demands through scalable and innovative manufacturing solutions.

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