Mof-enabled smart encapsulation for optimized micronutrient delivery
This innovative solution utilizes metal-organic frameworks (MOFs) to encapsulate micronutrients in dietary supplements, enhancing stability and absorption. MOFs' tunable structures allow for pH-responsive release, improving bioavailability and efficacy of vitamins and minerals.
Overview
This solution introduces a cutting-edge approach to nutrient delivery using metal-organic frameworks (MOFs) as encapsulation carriers for dietary supplements. MOFs provide a high surface area and tunable pore sizes that protect sensitive vitamins and minerals from degradation in the digestive tract. This system ensures pH-responsive and targeted nutrient release, optimizing absorption and enhancing bioavailability. By utilizing food-grade, GRAS-listed components, the MOF system is compatible with standard supplement formats, offering a safe and scalable method for delivering micronutrients effectively.
Technical specifications
Key features:
- High surface area MOFs enable efficient encapsulation of micronutrients.
- Tunable pore sizes and chemical versatility allow for stabilization and protection of sensitive vitamins and minerals.
- Functionalization for pH-responsive or targeted release ensures optimal intestinal absorption.
- Compatible with various supplement formats, including tablets, capsules, and gummies.
- Utilizes food-grade, biocompatible MOF components for safety and scalability.
Technology readiness level
Currently at Technology Readiness Level 2, this solution is in the early stages of development. Phase 1 involves identifying suitable MOFs through bibliographic research, while Phase 2 focuses on synthesis, in vitro testing, and small-scale animal studies to assess encapsulation efficiency, nutrient protection, and bioavailability under simulated gastrointestinal conditions.
About Calistair
Founded in 2014, Calistair is a material science and chemical technology company specializing in innovative air purification and contaminant capture. Its core technology, the Calistair Technology, utilizes a proprietary non-thermal catalysis method integrated into modular reactors. These reactors combine honeycomb structures impregnated with advanced materials—such as zeolites and metal-organic frameworks (MOFs)—with UV-C activation. This process generates hydroxyl and superoxide radicals that effectively mineralize and destroy airborne biocontaminants, volatile organic compounds (VOCs), chemical pollutants, and viruses, including coronaviruses, without producing toxic by-products like ozone. The technology is designed for scalability and high-velocity airflow, allowing it to be retrofitted into ventilation systems or utilized in dedicated air purification units.
Calistair's solutions are engineered to improve safety standards in environments ranging from hospitals, laboratories, and cleanrooms to industrial buildings and public spaces. The company serves a global client base, including medical facilities requiring high particulate cleanliness standards and industrial sectors focused on emission reduction and gas purification. Since its inception, the company has received recognition for its contributions to public safety, notably during the COVID-19 pandemic, and continues to advance its material science research for applications in energy storage, defense, and pharmaceutical sectors. Headquartered in France, Calistair maintains integrated R&D and manufacturing capabilities to support the implementation of its air decontamination technology across diverse industrial and medical applications.
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