Multi-functional water-based barrier against mosquito bites

Technology
In development
University

A novel water-based barrier using Cellulose Nano Crystals (CNC) that disperses mosquito repellents, providing long-lasting protection and reducing attractiveness. It offers multiple application forms and is validated through ongoing clinical trials.

Overview

This innovative solution leverages the unique properties of Cellulose Nano Crystals (CNC) to create a multi-functional water-based barrier that protects against mosquito bites. CNCs are bio-based materials known for their strength and ability to self-assemble into transparent films. They serve as a chemical camouflage when applied to skin, reducing attractiveness to mosquitoes. This technology allows for the dispersion of both volatile and non-volatile mosquito repellents, extending their duration and enhancing spatial repellency.

Technical specifications
  • Cellulose Nano Crystals (CNC): Bio-based, self-assembling into strong, transparent films.
  • Application Forms: Available in gel, spray, and roll-on.
  • Mechanism: CNC disperses repellents in water, which upon evaporation, leads to self-assembly and slow-release of trapped repellents.
  • Repellents Tested: Includes both natural and synthetic options like citronella and DEET.
  • Testing: Conducted on human skin and artificial systems; currently under multi-subject clinical trials.
Technology readiness level

This technology has reached TRL 4, indicating it is beyond proof of concept and is undergoing validation in controlled environments. Future clinical trials aim to assess its efficacy, consumer acceptance, and comparability to existing market products.


About Hebrew University of Jerusalem

The Hebrew University of Jerusalem is a comprehensive public research university with multiple campuses in Jerusalem and an agricultural campus in Rehovot. Its integration with Hadassah’s university hospitals enables clinical studies, access to varied patient populations, and co‑located research that accelerates translation. Industry engagement runs through Yissum, the university’s tech‑transfer company, managing IP, licensing, startup creation, and sponsored research agreements. Research is supported by competitive national funding and international programs, including European Union frameworks.

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