Kalasalingam Academy of Research and Education

Nano-encapsulated antifungal volatile seed treatment for pythium control

Technology
In development
Company

Innovative nano-formulation utilizing Mentha-derived volatiles immobilized in graphene oxide to suppress Pythium pathogens, enhance crop growth, and promote soil health. Demonstrates significant disease incidence reduction and improved plant performance.

Overview

The nano-encapsulated antifungal volatile seed formulation is designed to control soil-borne plant pathogens such as Pythium aphanidermatum and Fusarium oxysporum. It leverages volatile organic compounds (VOCs) derived from Mentha leaves, including carvone, caryophyllene, limonene, and menthol, to suppress pathogen activity. The combined VOC profile—particularly carvone—aims to reduce pre- and post-emergence damping off in crops, promote growth, and activate defense mechanisms in pathogen-rich soils.

Technical specifications

The formulation uses graphene oxide to immobilize Mentha-derived volatiles, enabling sustained release of antifungal compounds directly at the infection site in the soil. Reported performance includes disease incidence reduction of 88–89%, along with improved seed germination and increased plant height, contributing to higher crop yield. The approach is also intended to support soil microbiome health as part of the overall crop protection strategy.

  • Key components: Carvone, Caryophyllene, Limonene, Menthol
  • Carrier: Graphene oxide for sustained release
  • Benefits: Significant disease reduction, improved germination, enhanced crop yield, soil microbiome promotion
Technology readiness level

Currently at TRL 5, the technology has undergone laboratory testing and is moving toward greenhouse trials and multi-location field trials to further validate efficacy and support scaling up to bulk production. Future validation steps will include compliance with EU regulations and preparation for market entry.

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