Nanoformulated protein bioinsecticide for rice pest management
A novel nanoformulated protein-based bioinsecticide using Oryzacystatin-II encapsulated in chitosan nanoparticles to target brown planthopper in rice. This solution offers enhanced stability, bioavailability, and eco-friendly pest control.
Overview
The nanoformulated protein bioinsecticide is an innovative solution targeting the brown planthopper, a major pest affecting rice crops. Utilizing Oryzacystatin-II, a rice-derived cysteine protease inhibitor, this bioinsecticide is encapsulated in chitosan nanoparticles. This formulation enhances the stability and bioavailability of the protein, allowing for effective foliar application that improves penetration and persistence on rice plants. The mechanism of action involves inhibiting gut proteases in the pest, leading to impaired digestion, starvation, and mortality, thereby offering a sustainable and environmentally friendly alternative to chemical pesticides.
Technical specifications
- Nanoencapsulation: Oryzacystatin-II is encapsulated in chitosan nanoparticles, enhancing stability and enabling controlled release.
- Application: Designed for foliar application for enhanced plant penetration and persistence.
- Mechanism of Action: Inhibits digestive enzymes in the brown planthopper, leading to starvation and mortality.
- Eco-friendly: Uses rice-derived protein and biodegradable chitosan, ensuring minimal off-target effects and environmental impact.
Technology readiness level
Currently at TRL-4, this bioinsecticide formulation has been validated in controlled environments. The next phase involves optimizing nanoencapsulation parameters, characterizing nanoparticles, and conducting efficacy trials under glasshouse and field conditions. Supported by sponsored research, the solution aims to advance to TRL-5/6 with larger-scale trials and regulatory preparations.
About Sathyabama Institute of Science and Technology
Sathyabama Institute of Science and Technology is a private deemed‑to‑be university in Chennai with a large residential campus and a comprehensive research and education profile. For corporate partners, the on‑campus research park and makerspaces enable pilot‑scale prototyping and testing alongside faculty expertise. A Department of Science and Technology–supported technology business incubator provides incubation, mentorship, and seed support, creating a streamlined path from lab results to venture‑ready solutions. Integration with a general hospital and an affiliated dental college enables clinical collaboration, validation, and access to diverse patient populations. Research is backed by competitive national funding, including programs of India’s Department of Science and Technology, and supported by dedicated innovation and technology transfer infrastructure.
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