Nanofrogskin: A multifunctional patch for enhanced tissue regeneration

Technology
Conceptual
Company

NanoFrogSkin is an innovative wound healing patch utilizing nano collagen from frog skin to enhance tissue regeneration, reduce inflammation, and improve wound closure compared to standard dressings. It features a multi-layered structure with antimicrobial and hydrating properties.

Overview

NanoFrogSkin is a cutting-edge wound healing solution that leverages the unique properties of nano collagen derived from frog skin. This multifunctional patch is designed to significantly enhance tissue regeneration, reduce inflammation, and improve wound closure rates. By integrating advanced biomaterials in a multi-layered patch, NanoFrogSkin offers a superior alternative to conventional wound dressings, promoting faster and more effective healing.

Technical specifications

The NanoFrogSkin patch comprises several innovative layers:

  • Nano collagen base layer: Derived from frog skin, this layer promotes cell proliferation, migration, and differentiation, essential for wound healing.
  • Antimicrobial peptide-infused layer: Provides protection against common wound pathogens, enhancing the patch's efficacy in preventing infections.
  • Hydrating polymer layer: Incorporates substances like hyaluronic acid to maintain moisture, crucial for optimal wound healing.
  • Controlled release technology: Ensures that active ingredients are delivered at a consistent rate to maximize therapeutic benefits.

The patch is being optimized for flexibility, adherence, and moisture retention to ensure comfort and effectiveness.

Technology readiness level

Currently at Technology Readiness Level 2, NanoFrogSkin is undergoing in vitro studies to assess its biocompatibility, cell proliferation, migration efficacy, and antimicrobial properties. In vivo studies in animal models are planned to further validate its performance in reducing inflammation, enhancing tissue regeneration, and ensuring safety compared to standard wound dressings.


About Cuprina Holdings

Cuprina Holdings is a Singapore-based biomedical and biotechnology company focused on harnessing entomology-driven solutions for healthcare, agriculture, and waste management. Its primary medical innovation is MEDIFLY, a bio-dressing therapy utilizing live, medical-grade Lucilia cuprina maggots. These products are designed to clean wound beds and treat chronic wounds, offering a clinically effective and cost-conscious alternative to traditional debridement methods. By integrating biological insights into industrial processes, the company also explores broader applications for its technologies in sustainable development and circular economy solutions.

The company serves healthcare providers, clinics, and hospitals by providing end-to-end wound care solutions intended to improve patient quality of life and reduce the frequency of amputations. Their medical products have demonstrated significant clinical efficacy in local studies, including high rates of limb salvage and wound closure for complex patient populations. Through its leadership in biotechnology and insect-based applications, Cuprina addresses critical medical challenges while simultaneously expanding its capabilities into urban farming and sustainable resource management, aiming to build a future-fit organization that benefits both communities and the planet.

Halo home
Partner smarter. Move faster.
Get new partnering requests
delivered to your inbox.