Natural anti-microbial compounds inhibiting yeast and mold spoilage
A set of natural anti-microbial compounds designed to inhibit spoilage yeasts and molds, including Z. bailii and Aspergillus strains. Compounds derived from plant sources and fermentation processes show in vitro efficacy in broth dilution assays at concentrations as low as 125 ppm. The approach is being optimized for food shelf-life applications and aims to provide non-antibiotic preservation options.
Overview
A range of natural anti-microbial compounds has been developed to inhibit the growth of spoilage yeasts and molds. These compounds, derived from plant sources and fermentation processes, target strains such as Zygosaccharomyces bailii, Candida parapsilosis, and Aspergillus species. The primary goal is to enhance the shelf life of food products by mitigating spoilage caused by these microorganisms.
Technical specifications
Key features:
- Derived from natural sources, including plant secondary metabolites and fermentation of wild-type strains
- Effective against Zygosaccharomyces, Candida, Dekkera, and Saccharomyces yeasts, as well as Aspergillus and Penicillium molds
- Demonstrated efficacy in broth dilution assays at concentrations as low as 125 ppm
- Free from antibiotic compounds, aligning with consumer demand for natural preservatives
Technology readiness level
This technology is at TRL 5, having demonstrated efficacy in relevant environments in vitro. The next steps involve further validation against spoilage strains and optimization for shelf-life extension in food products.
About AnalytiCon Discovery GmbH
AnalytiCon Discovery is a research and development company specializing in natural product chemistry and small molecule compounds. Based in Potsdam, Germany, the company provides end-to-end services for the pharmaceutical, cosmetic, food, and agricultural sectors. Their capabilities span the entire discovery value chain, including the establishment of proprietary substance libraries, identification of active ingredients, synthetic optimization, and commercial-scale production. The company leverages an integrated approach that combines microbiology, natural product isolation, state-of-the-art analytical technologies like NMR and LC/MS, and advanced screening platforms. Since 2013, AnalytiCon has operated as a member of the BRAIN Biotech Group, utilizing specialized laboratories and a team of experts to transform natural molecules into viable, innovative products.
By offering deep expertise in natural product-based discovery, AnalytiCon serves as a critical partner for organizations seeking to overcome the complexities of medicinal chemistry and substance development. They solve significant industry challenges by providing high-quality, fully elucidated compound collections that expedite preclinical discovery projects and research into novel therapeutic targets. Their track record includes numerous successful collaborations with global pharmaceutical and consumer goods companies, focusing on applications such as drug discovery, sugar and calorie reduction, and natural preservation ingredients. Through their combination of technical competence and solution-oriented project management, they enable partners to accelerate the development of sustainable, bio-based products for diverse global markets.
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