Nitric oxide neuropathy relief technology

Technology
In development
Company

Noxsano's patented technology offers a controlled delivery of nitric oxide for neuropathy relief, minimizing systemic exposure and off-target effects. This platform provides benefits such as vasodilation, anti-inflammatory action, and nerve regeneration, making it ideal for treating nerve pain.

Overview

Noxsano's innovative neuropathy relief technology leverages its patented platform to generate nitric oxide (NO) electrochemically at the point of use. This system is designed to deliver sustained, biologically relevant levels of NO, which is crucial for treating nerve pain associated with peripheral neuropathy. Unlike traditional NO donor compounds, Noxsano's platform provides controlled NO delivery, minimizing systemic exposure and off-target effects. This makes it a highly promising solution for nerve pain treatment.

Technical specifications
  • Controlled NO Delivery: Generates NO at precise concentrations tailored for nerve pain relief.
  • Application Versatility: Can be applied topically or via a device directly to peripheral nerve beds.
  • Proven Efficacy: Independent studies show benefits in granulation, angiogenesis, antimicrobial action, and tissue perfusion.
  • Mechanistic Benefits: Vasodilation improves blood flow, anti-inflammatory signaling reduces inflammation, and NO pathways alleviate pain and promote nerve regeneration.
Technology readiness level

This technology is currently at TRL 6, indicating it has been demonstrated in a relevant environment. Future validation plans include optimization using animal models followed by clinical testing, aiming for market introduction within 18-24 months.


About Noxsano Inc

Noxsano is a wound care company that develops medical treatments for human and veterinary applications by delivering nitric oxide to the wound bed. Their primary technology platform, marketed as Restore, utilizes pads and hydrogels that are activated with water or saline to generate nitric oxide at the point of use. This technology is designed to speed healing, prevent infection, and restore normal healing processes in both acute and chronic wounds, including surgical incisions and complex injuries. By delivering potent nitric oxide therapy locally, the products offer a convenient and cost-effective alternative to traditional wound management techniques.

The company’s approach is particularly valuable for veterinary professionals treating difficult wounds where traditional surgical intervention may be challenging, costly, or not an option. Clinical testimonials and case studies demonstrate the utility of Restore products in managing severe injuries, including de-gloved paws, burns, and chronic wounds that have failed to heal with conventional treatments. By providing a non-toxic, easy-to-apply solution, Noxsano helps clinicians minimize bandaging and improve patient outcomes in outpatient and clinical settings, addressing a significant need in veterinary wound care.

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