Novel daily anti-plaque, anti-gingivitis treatment

PhytoLight is a novel oral care platform that combines a plant-derived photosensitizer formulation with a light-activation device to disrupt and inhibit dental plaque biofilm through a non-mechanical mechanism. The technology utilizes a proprietary Polygonum cuspidatum extract that, when exposed to visible blue light, generates localized photodynamic activity designed to target plaque-associated microorganisms and biofilm on tooth surfaces and along the gingival margin. Unlike traditional flossing approaches that rely primarily on mechanical removal, PhytoLight leverages a chemistry plus delivery system that can be incorporated into a simple 1-minute daily oral care routine before brushing.

The PhytoLight platform has completed multiple human clinical studies at Forsyth Institute in Boston, demonstrating significant improvements in gingival health and reductions in bleeding on probing, while maintaining an excellent safety profile. The technology is protected by an international patent portfolio covering photodynamic compositions, methods of use, and device technologies, and is supported by FDA Class II device registration and commercial manufacturing capabilities. We believe the platform represents a differentiated approach to plaque management and oral hygiene that aligns with P&G's interest in innovative solutions capable of disrupting biofilm formation, improving consumer compliance, and delivering meaningful oral health benefits beyond conventional mechanical cleaning methods.