Ph responsive smart particle materials for targeted oral care delivery

Overview

Smart Particle technology provides pH-triggered delivery for oral care actives. Porous silica microparticles encapsulate a range of active ingredients, including amino acids, minerals, and antioxidants. The particles are designed to remain inert until activated by a specific environmental trigger such as a change in pH, enabling release of active ingredients precisely when needed to enhance efficacy and stability in oral care products.

Technical specifications

Key Features:

• Encapsulation Technology: Uses porous silica microparticles to encapsulate a wide range of actives.
• Trigger-Based Release: Releases contents in response to environmental changes, specifically pH shifts.
• Compatibility: Can be incorporated into various matrices including gels, pastes, and liquids.

Application in Oral Care:

• Active Ingredients: Potential to encapsulate antigingivitis agents, prebiotics, and postbiotics for targeted oral health benefits.
• Stability and Performance: Aims to enhance the stability and performance of active ingredients in oral care formulations.

Technology readiness level

The Smart Particle technology is currently at Technology Readiness Level 3. The concept has been demonstrated with antigingivitis actives. Planned development activities include defining parameters, synthesizing custom Smart Particles, measuring properties, and scaling up production to kilogram levels for efficacy testing and commercialization.