Plant-derived bioactive peptides for anti-inflammatory and wound healing applications

Technology
In development
Company

Valogen Biosciences Ltd has developed a proprietary process to extract bioactive peptides from agri-food proteins, enhancing their anti-inflammatory and wound healing properties. This innovation accelerates wound healing by resolving inflammation and supporting cellular regeneration.

Overview

Valogen Biosciences Ltd introduces a groundbreaking solution using plant-derived peptides to enhance wound healing and anti-inflammatory responses. These bioactive peptides are extracted and hydrolyzed using a proprietary process that optimizes their yield and effectiveness. Known for their regenerative effects, these peptides accelerate the wound healing process by addressing the inflammatory phase, often prolonged due to bacterial infections. This innovative approach promises significant improvements in the treatment of recalcitrant or 'hard to heal' wounds.

Technical specifications

Key features:

  • Proprietary extraction and hydrolysis process for agri-food proteins.
  • Enhanced bioactivity including anti-inflammatory and regenerative effects.
  • Demonstrated increased keratinocyte viability and significant biomarker expression for wound healing.
  • Upregulation of glycolytic ATP production and proteostasis, crucial for healing.
  • Incorporation into hydrocolloid test patches for further validation.

Application:

  • Treatment of chronic wounds and autoimmune skin diseases like psoriasis and vitiligo.
  • Potential use in therapeutic formulations for enhanced skin regeneration.
Technology readiness level

Currently at TRL 4, this technology has been validated in laboratory settings with human dermal fibroblasts and is undergoing further in vitro validation studies using human keratinocytes. This stage involves assessing the anti-inflammatory effects in a controlled environment to simulate real-world applications in wound management.


About Valogen Biosciences Ltd

Valogen Biosciences Ltd is an agritech company that transforms underutilised agri-food side-streams, such as rapeseed meal, into high-value bioactive peptides. The company employs a proprietary, scalable process—developed through extensive research and pilot plant operations—to extract and purify these materials. Their technology allows for the creation of functional ingredients that serve as alternatives to traditional, lower-value applications of agricultural by-products, focusing on delivering scientifically validated, highly digestible, and allergen-free components. By leveraging circular economy principles, the company aims to convert waste streams into sustainable, high-value biorenewables.

The company provides innovative solutions for the nutrition, personal care, and medical sectors. Their bioactive peptides have demonstrated efficacy in various applications, including as hair conditioners in cosmetics, savoury flavour enhancers in food products, and agents with anti-inflammatory and wound-healing properties in healthcare. Valogen works with industrial partners and research institutions to validate their products and scale production, having progressed from laboratory concepts to functional pilot-scale manufacturing. Their business strategy relies on continuous R&D, strategic grants, and partnerships to support their transition toward larger, commercial-scale production facilities.

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