A cost-effective, low-toxicity plasmonic coating using bismuth nanoparticles for light-activated surface disinfection. Generates reactive oxygen species under visible light to kill bacteria and viruses, offering an environmentally friendly alternative to expensive gold and silver-based plasmonic materials for healthcare, public spaces, and high-touch surface applications.
This technology offers a novel approach to surface disinfection through a plasmonic coating based on bismuth nanoparticles. Unlike conventional disinfectants that require chemical agents or expensive precious metals, this coating harnesses light energy to generate reactive oxygen species (ROS) that actively destroy bacteria and viruses on coated surfaces. The use of bismuth provides significant advantages over traditional gold and silver plasmonic materials, including lower cost, reduced toxicity, and improved environmental compatibility.
The coating works by absorbing visible light through the surface plasmon resonance (SPR) effect in bismuth nanoparticles. This light absorption produces high-energy electrons and holes that generate highly reactive chemical radicals, which kill pathogens through oxidative damage to cell walls and internal structures. This approach provides a continuous, light-activated disinfection mechanism suitable for high-touch surfaces in healthcare facilities, public transportation, food processing environments, and consumer products.
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This technology is at an early research stage with proof-of-concept validation. Previous research has demonstrated that bismuth nanostructures exhibit plasmonic properties and can produce ROS under visible light illumination. Plasmonic silver nanostructures have already shown effectiveness as light-activated disinfectants in published studies, establishing the underlying mechanism.
Future validation plans include establishing baseline performance using silver nanoparticles against Escherichia coli and Staphylococcus aureus, synthesizing and characterizing bismuth nanoparticles with controlled size and shape, identifying ROS types through ESR spectroscopy, optimizing wavelength-dependent disinfection efficiency, and developing stable coating methods suitable for real-world surfaces. The project is positioned for sponsored research collaboration to advance toward practical coating formulations and commercial applications.
Duke University is a mid-sized, comprehensive private research university in Durham, North Carolina, anchored by a globally recognized academic medical center. Co-located campus and clinical facilities enable rapid bench-to-bedside translation, and shared core laboratories are accessible to external partners. Proximity to Research Triangle Park links Duke to a dense network of R&D-intensive companies, supported by centralized corporate engagement for sponsored research and talent pipelines. Research is supported by competitive federal funding from agencies such as NIH, NSF, DOE, and DoD. A dedicated technology transfer office supports IP strategy, licensing, startups, and industry collaboration.