Postbiotic solutions with immune properties from probi
Probi introduces Rham271h and M18 postbiotic solutions, offering anti-inflammatory benefits for oral and systemic health. These solutions are derived from the heat-inactivated versions of well-studied probiotic strains, suitable for diverse applications in oral care products.
Overview
Probi presents innovative postbiotic solutions, developed from the heat-inactivated versions of the L. rhamnosus 271 and BLIS M18 probiotic strains. These postbiotics offer significant anti-inflammatory benefits, crucial for both oral health and overall systemic well-being. Unlike traditional live probiotics, these postbiotic versions pose fewer challenges in application and can be seamlessly integrated into oral care products like mouthwashes, toothpastes, and lozenges. This versatility makes them ideal for developers seeking to enhance the health benefits of their products.
Technical specifications
- Rham271h: Derived from L. rhamnosus 271, Rham271h has demonstrated significant anti-inflammatory activity in the Caco-2/THP 1 leaky gut model, particularly increasing IL-10 levels while maintaining a balanced immune response.
- M18 Postbiotic: Currently undergoing proof-of-concept studies, this postbiotic is expected to offer similar benefits for oral health, focusing on gum and teeth care.
- Applications: Both solutions can be incorporated into various oral health products, providing a broad range of product development opportunities.
Technology readiness level
These postbiotic solutions have reached a technology readiness level of 8, indicating they are nearing commercial deployment. Ongoing and future studies will continue to validate their efficacy and broaden their application potential.
About Probi
Probi is a global, science-driven company that specializes in the research, development, and production of clinically documented biotic solutions. Founded in 1991 at Lund University in Sweden, the company operates across the entire biotics field, leveraging expertise in R&D, fermentation, and manufacturing to deliver high-quality ingredients and finished products. Probi distinguishes itself through a strong focus on scientific rigor, utilizing over 350 global patents and numerous peer-reviewed studies to validate the efficacy of its bacterial strains. As a vertically integrated player, it manages the complete value chain—from initial research and clinical trials to production and commercialization—ensuring that its products meet strict regulatory and GMP standards before reaching global markets.
By providing science-backed biotic solutions, Probi helps customers and partners address diverse health areas, including gut, immune, metabolic, and oral health. The company serves a global base, offering customized formulations and ingredient formats that help brands fulfill consumer demands for effective health products. Through strategic partnerships, global supply chain capabilities, and state-of-the-art manufacturing facilities, Probi empowers people to improve their health by managing their microbiome. Now a subsidiary of Symrise AG, the company continues to advance its mission of improving lives through the science of biotics, supported by a commitment to sustainability and ongoing innovation.
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