Probiotic bacteria encapsulation in multilayer systems for enhanced survival
Nanomik Biotechnology's innovative multi-layer encapsulation system enhances the survival and stability of probiotic bacteria in food and beverages. This technology ensures probiotics reach and colonize the large intestine, improving product functionality.
Overview
Nanomik Biotechnology presents an advanced encapsulation technology that enhances the stability and survival of probiotic bacteria such as Lactobacillus sp and Bifidobacterium sp in food and beverage products. This multi-layer encapsulation system, using food-grade biopolymers, ensures that probiotics can withstand low pH environments, processing temperatures, and storage conditions. Upon reaching the human digestive system, the encapsulated probiotics are released into the large intestine, aided by prebiotic inputs, to effectively colonize and provide health benefits.
Technical specifications
The encapsulation process involves a layer-by-layer (LbL) system where probiotics are encapsulated with their spores and prebiotic components. The first core layer contains probiotic bacteria with sporulation powder, dried using a Spray Dryer. The second layer, a prebiotic mix, coats the first layer and is dried again to form the LbL system. Biopolymers such as alginate, pectin, chitosan, zein, and WPI are used to create the optimal composition. This system has been tested to ensure the viability of Lactobacillus plantarum in simulated GI tract conditions, enabling it to reach log cfu levels of 10^7 and survive food processing temperatures up to 72°C.
Technology readiness level
The technology is currently at TRL 3, indicating that it has been validated in a laboratory environment. Further testing and optimization are planned to enhance its application in commercial food and beverage products.
About Nanomik Biotechnology
Nanomik Biotechnology is a Turkey-based company founded in 2014 that specializes in developing natural, microencapsulated preservation solutions for the agriculture, food, and animal health sectors. The company utilizes proprietary technology to discover and stabilize natural active ingredients, creating sustainable alternatives to traditional chemical and synthetic substances. By employing patented microencapsulation techniques, Nanomik enhances the stability and efficacy of these biological actives, ensuring their performance in various environmental conditions. This technological approach allows for the creation of residue-free products that maintain product quality while addressing environmental and regulatory standards.
The company’s solutions are designed to protect crops, food products, and animal health, aiming to significantly reduce food spoilage and waste. By providing effective, nature-derived alternatives to hazardous chemicals, Nanomik helps producers meet the stringent biocide regulations in markets including the United States, Europe, and the Middle East. Through extensive international field trials and ongoing R&D, the company has demonstrated the viability of its solutions as they transition from pilot applications to full-scale commercialization, supported by international investment and strategic growth initiatives.
Inquire about this partnering listing
Industry applications
delivered to your inbox.