Rapid DMF mixing and micro-dosing platform for 100 ml formulations
Innovative digital microfluidic platform for precise formulation mixing and dosing. Utilizes programmable electrode paths for droplet manipulation, ensuring high accuracy and no contamination. Ideal for pharmaceutical and chemical applications.
Overview
The rapid DMF mixing and micro-dosing platform offers a revolutionary approach to formulation mixing and dosing. At its core, the platform leverages digital microfluidics (DMF) to achieve precise and repeatable mixing of liquid additives. This technology ensures the creation of homogenous mixtures in seconds, by manipulating droplets on a single-use cartridge. The innovative system allows for the seamless transfer of additives into 100 mL base formulations, ideal for applications in pharmaceuticals and chemicals.
Technical specifications
- Key features:
- Utilizes digital microfluidics for programmable droplet dispensing and mixing
- Single-use DMF cartridges ensure zero cross-contamination
- Precise dosing accuracy with electrostatic metering (±2%)
- Handles droplet sizes from 5–10 µL, mixed to 20–100 µL targets
- Enables rapid mixing and dosing within a 100 mL formulation
- Incorporates real-time electrical monitoring and closed-loop correction for reproducibility
- Single-use components eliminate dead volume and carryover risks
Technology readiness level
This platform is currently at Technology Readiness Level 6, with a validated DMF ecosystem already applied to automated, clinically relevant workflows. Ongoing validation is planned to further refine cartridge materials, optimize dosing and mixing parameters, and demonstrate multi-recipe operation for pilot-ready deployment.
About Blue Ocean Technologies
Blue Ocean Technologies is a Toronto-based biotech startup specializing in digital microfluidics (DMF) for rapid, point-of-care diagnostics. Founded in 2022 as a spinout from the University of Toronto, the company develops automated testing systems designed for high-stakes environments, such as emergency medicine and trauma care. By utilizing AI-driven detection algorithms and compact hardware, their platform aims to deliver lab-quality results in minutes using low-cost, disposable cartridges. The company’s capabilities were further strengthened by the acquisition of Sci-Bots, an expert in microfluidic hardware and the developer of the DropBot, an open-source digital microfluidic controller used globally by academic and industrial researchers.
The company addresses the critical need for fast, bedside diagnostics to reduce the burden on centralized healthcare infrastructure. Beyond their core diagnostic development, they provide R&D consulting and custom microfluidic system design for sectors including life sciences, agriculture, and industrial applications. By offering end-to-end support—from system design and prototyping to software integration—Blue Ocean Technologies helps partners overcome R&D limitations and transition complex microfluidic concepts into market-ready products. Their approach streamlines workflows, improves experimental reproducibility, and enables real-time decision-making in clinical and remote settings.
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