Cerzos-CONICET

Recombinant hsp90 and kazal inhibitor proteins for plant immune modulation and pathogen defense

Technology
Conceptual
University

Recombinant proteins from the Hsp90 family and Kazal-type serine protease inhibitors designed to modulate immune responses in plants and provide antifungal and bacteriostatic protection against phytopathogens.

Overview

This solution offers two families of recombinant proteins engineered for agricultural biotechnology applications. The first targets the 90-kDa heat shock protein (Hsp90) family, leveraging its well-documented role as an immune response modulator and adjuvant to enhance plant defense mechanisms. The second focuses on Kazal-type serine protease inhibitors, which provide bacteriostatic and antifungal activity to protect plants against phytopathogens. Together, these proteins represent a dual-strategy approach to strengthening plant immunity and managing crop diseases.

Technical specifications

Hsp90 recombinant proteins:

  • Designed to modulate immune responses in plants
  • Function as immune response modulators with adjuvant properties
  • Recombinant expression enables scalable production and consistent quality

Kazal inhibitor recombinant proteins:

  • Engineered to elicit protective responses against phytopathogens
  • Inhibit serine proteases, disrupting pathogen virulence mechanisms
  • Exhibit bacteriostatic and antifungal activity

Both protein families are produced through recombinant technology, allowing for controlled expression, purification, and formulation tailored to specific agricultural applications.

Technology readiness level

This is an early-stage research offering. The proposed proteins have been conceptually designed based on established scientific knowledge of Hsp90 immune modulation and Kazal inhibitor antimicrobial properties. Further validation through controlled laboratory and greenhouse studies is needed to confirm efficacy, optimal delivery methods, and field performance before commercial deployment.

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