Rhinifilm botanica: botanical nasal spray for allergen protection

Technology
Conceptual
Company

RhiniFilm Botanica is an innovative nasal spray that forms a protective biofilm upon contact with the nasal mucosa. Utilizing natural polysaccharides, it offers a non-pharmacological barrier against allergens and irritants, providing relief and comfort for allergic rhinitis sufferers.

Overview

RhiniFilm Botanica is a groundbreaking pharmaceutical innovation designed to tackle allergic rhinitis by leveraging the natural properties of botanical polysaccharides. This nasal spray forms a protective biofilm directly on the nasal mucosa, acting as a physical barrier to trap airborne allergens and irritants. By selecting non-pharmacological film-formers, this solution aligns with the natural concept preferred in regulatory frameworks, providing a safer alternative to traditional pharmacological interventions. This approach not only helps relieve symptoms of allergic rhinitis but also offers comfort through botanical extracts, making it a compelling solution for those seeking natural allergy protection.

Technical specifications
  • In-situ gelling: The spray is formulated with vegetable/botanical polysaccharides that gel upon application to the nasal mucosa, forming a durable biofilm.
  • Allergen barrier: The biofilm acts as a physical shield, effectively trapping allergens such as pollen and indoor irritants.
  • Botanical soothing: Incorporates botanical components like chamomile and elderflower for added comfort and soothing effects.
  • Development tasks: Includes polysaccharide selection for optimal gel strength, prototype development, in vitro testing for mucoadhesion and allergen-blocking efficacy, and pre-clinical validation.
Technology readiness level

Currently, RhiniFilm Botanica is at Technology Readiness Level 3, indicating that it is in the early stages of development with ongoing formulation and prototype testing. The project is poised to advance through in vitro testing and pre-clinical validation, with regulatory pathways being addressed in parallel.


About Plinius Labs

Plinius Labs specializes in natural chemistry, providing research services and developing bio-based ingredients for food, personal care, and premium applications. Founded in 2021 in Belgium, it focuses on green substitution of ingredients and sustainable innovation.

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