Self-emulsifying systems for micro- and nanoencapsulation of bioactive compounds
Innovative self-emulsifying systems for encapsulating hydrophobic bioactive compounds, enhancing therapeutic efficacy through stable micro- and nanoemulsions with biodegradable surfactants.
Overview
This technology offers a novel approach to encapsulating hydrophobic bioactive compounds through self-emulsifying systems. These systems enable the rapid formation of stable micro- and nanoemulsions, which enhance the therapeutic efficacy of the encapsulated active ingredients. By utilizing biodegradable surfactants, the system ensures environmental safety and minimal energy consumption during the encapsulation process.
Technical specifications
Key features:
- Comprises an anhydrous isotropic blend of multiple surfactants and a hydrophobic compound.
- Forms emulsions with droplet sizes ranging from 15 to 500 nm upon gentle agitation with water.
- High kinetic stability due to interfacial turbulence generated by surfactant interaction with water.
- Features biodegradable surfactants with varying HLB values to optimize droplet formation.
- Utilizes high-frequency dielectric spectroscopy for droplet stability characterization.
Technology readiness level
The technology is at TRL 4, having been validated in laboratory settings. Future plans include optimizing surfactant combinations and testing in cell cultures and animal models to assess therapeutic effects on diseases like cancer.
About Tecnológico de Monterrey
Tecnológico de Monterrey is a leading private, multi-campus research university in Mexico, recognized for entrepreneurship and industry collaboration. Its Monterrey headquarters anchors an urban innovation district with open lab space, prototyping, and shared testing facilities that welcome corporate collaborators. An integrated health system supports clinical research and translation, while structured internships and challenge-driven partnerships connect companies with faculty and student talent year-round. Research is supported by competitive federal funding through Mexico’s national science and technology council, along with industry contracts and international sponsors. A dedicated technology transfer office manages IP, licensing, and startup formation.
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