Simultaneous zinc and calcium detection with dPAD-integrated MIPs

Overview

This cutting-edge device offers simultaneous detection of zinc (II) and calcium (II) ions using a distance-based paper device (dPAD) integrated with molecularly imprinted polymers (MIPs). The technology focuses on separating analytes through a structured flow from the sample zone to the extraction and detection zones. MIPs are employed for their minimal interaction with other metal molecules, enhancing the specificity and selectivity of the detection process. This solution is particularly valuable for sectors requiring precise metal ion analysis, such as environmental monitoring and biochemical research.

Technical specifications

• Detection Method: Utilizes a distance-based paper device (dPAD) for analyte separation.
• Extraction & Detection Zones: Embedded with indicators that change color upon interaction with target analytes.
• Molecularly Imprinted Polymers (MIPs): Coated on extraction zones for specific binding of zinc and calcium ions.
• Colorimetric Output: The presence of analytes induces a color change correlating with their concentration.
• Optimization Parameters: Includes polymer concentrations, analyte template concentrations, polymerization times, and pH conditions.

Technology readiness level

This technology is at Technology Readiness Level 2, indicating that it has been validated through analytical methods and is in the early stages of development. Further optimization and real-sample analysis are planned to advance the device towards practical applications.