Small molecule therapeutics for treatment of skin inflammation (eczema, psoriasis)
Many skin diseases have their origin in inflammatory response. Our group has been studying the role of the enzyme NEU1 in inflammation, and have developed clear mechanistic data supporting its influence on T cell activation. Using genetic knock-outs (murine) and ex vivo models (human) we have confirmed that genetic or pharmacological inhibition of NEU1 blocks disease severity in double blinded studies. We are seeking partners to develop these candidates for pre-clinical or IND.
About University of Alberta
The University of Alberta is a large, comprehensive public research university in Edmonton with multiple campuses and a strong applied research culture. Industry engages through co-located labs and pilot-scale facilities, as well as established co-op and internship programs that place talent with partners year-round. Integration with Alberta’s province-wide hospital system supports clinical research and accelerates translation. Companies also benefit from proximity to regional industry clusters and collaboration hubs on and near campus for joint R&D and prototyping. Supported by NSERC, CIHR, SSHRC, and Canada Foundation for Innovation funding—plus provincial and industry support—the tech transfer office manages IP, licensing, and startup formation with streamlined sponsored-research agreements.
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