Smart hybrid microparticles with biocompatible adhesion

Technology
In development
University

A novel formulation of hybrid microparticles utilizing biocompatible physical adhesion for enhanced product durability and performance. Suitable for biomedical delivery, diagnostics, and antimicrobial applications with TRL 5.

Overview

This innovative technology involves the development of smart hybrid microparticles using a biocompatible physical formulation and adhesion process. Unlike traditional chemical cross-linking, which can be cytotoxic, this method employs polyelectrolytic complexation and non-covalent interactions, ensuring stability and strong adhesion to various surfaces. The result is a significant enhancement in particle deposition and retention, which can improve the durability and performance of products in diverse applications such as biomedical delivery and environmental protection.

Technical specifications

Key features:

  • Utilizes physical cross-linking in aqueous environments to avoid cytotoxic chemical processes
  • Incorporates polyelectrolytic complexation and non-covalent interactions for biocompatibility
  • High local concentration of encapsulated active functional cargo, including small molecules and nanoparticles
  • Applies advanced surface characterization techniques like in-situ XPS, AFM, DLS, SEM, and EDS
  • Proven applications in biomedical therapeutics, diagnostics, antimicrobial cleaning solutions, and surface protection
Technology readiness level

This technology is at a TRL 5, indicating that it has been validated in a relevant environment. The team is actively collaborating with industry partners to tailor formulations for specific applications, aiming for further development and commercialization.


About University of North Texas

The University of North Texas is a comprehensive public research university in Denton, part of the UNT System, serving a large and diverse student body with broad academic programs. A dedicated research campus brings engineering and science together with shared user facilities, advanced instrumentation, prototyping spaces, and technology transfer support that speed collaboration with industry. Its Dallas–Fort Worth location offers ready access to major corporate R&D, suppliers, and testing partners, supported by project-based engagements, internships, and sponsored capstones. Research is backed by competitive federal funding from agencies such as the National Science Foundation, Department of Defense, and Department of Energy, alongside state and industry support.

Halo home
Partner smarter. Move faster.
Get new partnering requests
delivered to your inbox.