Sulfur-oxidation enzyme technology for halitosis control
Innovative Sox enzyme cocktail platform biochemically degrades volatile sulfur compounds, offering a microbiome-friendly solution for long-lasting breath control without masking odors or using harsh chemicals.
Overview
The sulfur-oxidation enzyme technology offers a groundbreaking approach to controlling halitosis by biochemically degrading volatile sulfur compounds (VSCs) such as hydrogen sulfide into non-volatile sulfate. Unlike traditional methods that mask odors or eliminate bacteria indiscriminately, this technology transforms malodorous molecules directly, providing a microbiome-friendly solution. It is suitable for non-rinse formats like mucoadhesive gels, oral films, and denture systems, enabling extended residence and multi-hour odour control.
Technical specifications
Key features:
- Recombinant Sox enzyme cocktail: Catalytically converts VSCs into odourless sulfate.
- Non-probiotic, non-alcohol, non-antibiotic: Compatible with a range of non-rinse formats.
- Microbiome-friendly: Maintains the natural oral flora while controlling bad breath.
- Extended contact formats: Designed for mucoadhesive gels, oral films, and denture inserts.
- Stability and activity: Stabilization systems support enzyme activity and shelf stability.
Technology readiness level
The technology is currently at TRL 3, indicating active research and development with validation in laboratory settings. Future plans include optimizing enzyme cocktails, validating performance in biofilm systems, and conducting pilot human studies, with regulated pilot product estimated in 24-30 months.
About Sarvotham Care Ltd
Sarvotham Care Limited is an established Contract Development and Manufacturing Organization (CDMO) and Contract Manufacturing Organization (CMO) that provides comprehensive end-to-end solutions for the healthcare, personal care, and home care industries. The company manages the full product lifecycle, including formulation research and development, clinical and pre-clinical services, and commercial-scale manufacturing. Its manufacturing capabilities span various dosage forms, such as granules, powders, tablets, capsules, liquids, creams, and gels. Sarvotham emphasizes technology-driven processes, regulatory compliance, and international quality standards, supported by internal laboratories equipped for advanced microbiological and chemical analysis.
The company serves as a strategic partner to multinational corporations and large Indian firms, focusing on on-time delivery and consistent quality. By offering private label services, Sarvotham enables clients to develop and market their own branded products while leveraging the company's manufacturing expertise and R&D infrastructure. Committed to sustainability and professional integrity, Sarvotham integrates environment, health, and safety (EHS) protocols into its operations, striving to meet both local and global market demands through scalable and innovative manufacturing solutions.
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