Targeted probiotics delivery via dual encapsulation technology

Technology
Conceptual
Company

This innovative dual encapsulation technology enables targeted probiotics release in the gastrointestinal tract. It features a pH-responsive outer shell, ensuring stability and efficacy, while minimizing taste impact in beverages.

Overview

This dual encapsulation technology is designed to deliver probiotics effectively to the gastrointestinal tract. Utilizing a pH-responsive hydrogel core, the system ensures that probiotics are protected in the acidic stomach environment and released only when reaching the intestinal tract, where pH levels are appropriate. This approach not only maintains probiotic viability but also minimizes sensory impact in beverage applications, making it ideal for health-focused consumer products.

Technical specifications

Key features:

  • Hydrogel Core: Encapsulates probiotics and prebiotics, forming a stable environment for nutrient supply and viability.
  • Oxidation Protection: An oil layer protects the inner core from oxidation, enhancing stability.
  • pH-Responsive Shell: The outer shell is designed to dissolve at specific pH levels (6-7), ensuring targeted release in the intestines.
  • Minimal Organoleptic Impact: Ensures that the taste and texture of beverages remain unaffected.
Technology readiness level

Currently at Technology Readiness Level 3, this technology has shown promise in controlled lab environments. Future validation will involve optimizing the encapsulation process, assessing techno-economic feasibility, and conducting sensory evaluations. Lipidware Sdn Bhd is seeking partnerships to support pilot-scale production and regulatory compliance guidance.


About Lipidware Sdn Bhd

Lipidware Sdn Bhd is a Malaysian biotechnology company founded in 2017 as a university startup from Universiti Putra Malaysia (UPM) through the Putra Science Park InnoHub Programme. The company specializes in translating academic research into commercialized skincare solutions, most notably its REMDII brand. Developed by researchers in biotechnology and biochemistry, the company’s core innovation involves a patented bioactive delivery system that utilizes full-spectrum tocotrienols—a form of Vitamin E—to provide targeted anti-inflammatory and barrier-repair properties for sensitive and eczema-prone skin. This research-driven approach includes rigorous independent testing and ethics-approved human clinical trials to ensure safety and efficacy as a steroid-free alternative for individuals of all ages.

Beyond product development, Lipidware plays a significant role in community education and support through the Malaysia Eczema Support Community (MESC), which provides resources and guidance for patients and caregivers. The company’s efforts bridge the gap between clinical science and practical health management, addressing skin conditions such as atopic dermatitis, psoriasis, and actinic keratosis. Through its commitment to real science, Lipidware has earned numerous national and international accolades for innovation and commercialization, successfully moving university-backed breakthroughs from the laboratory to pharmacy shelves to improve patient quality of life.

Halo home
Partner smarter. Move faster.
Get new partnering requests
delivered to your inbox.