We offer a human-relevant, ultra-sensitive platform to detect subclinical skin responses before visible irritation occurs. The approach integrates non-invasive biomarkers (e.g., tape-stripping cytokines), biophysical measurements (TEWL, microcirculation, hyperspectral imaging), and data-driven analysis to capture early microinflammatory and barrier changes under low-dose exposure conditions (<0.01 mg/cm²).
Unlike conventional irritation testing that relies on visible endpoints, this system enables quantitative differentiation of ultra-mild formulations and identification of previously undetectable biological response thresholds. The platform has been validated in laboratory settings and is designed for rapid deployment (2–3 months) in collaborative industry projects.
We are seeking partners for co-development, validation, and application in cosmetic and dermatological product testing, with the goal of transforming irritation assessment into predictive, decision-grade evaluation.
Universitas Muhammadiyah Jember is a private, multi-faculty comprehensive university founded in 1981 and rooted in Muhammadiyah’s education network. Its campus combines teaching and research laboratories with agricultural trial facilities, health-training infrastructure, and applied technical facilities, giving external partners practical points of engagement. The university’s LPPM coordinates research, publications, community engagement, and external collaboration, while an entrepreneurship incubator supports student and alumni startups and small businesses. Research is supported through competitive national higher-education and research funding, with digital systems used to manage proposals and partnership activity.