VSC BLOCK: enzyme-targeted halitosis control technology
VSC BLOCK™ offers a precision solution for halitosis by inhibiting methionine gamma-lyase, an enzyme responsible for sulfur gas production. This approach targets malodour at its biochemical source without disrupting the oral microbiome, suitable for oral films and lozenges.
Overview
VSC BLOCK™ is an innovative solution for controlling halitosis by targeting the biochemical root cause of malodour. Unlike conventional methods that merely mask bad breath, VSC BLOCK™ inhibits methionine gamma-lyase (MGL), a key enzyme responsible for producing volatile sulfur compounds (VSCs) such as hydrogen sulfide and methyl mercaptan. This targeted approach ensures effective malodour control while maintaining the balance of the oral microbiome. The technology is designed for integration into portable oral films or lozenges, providing precision and convenience for users seeking longer-lasting breath freshness.
Technical specifications
Key features:
- Inhibits methionine gamma-lyase (MGL) to reduce sulfur gas formation
- Targets the biochemical source of malodour for effective control
- Designed for low-dose, localized delivery via oral films or lozenges
- Preserves the broader oral microbiome, preventing disruption
- Suitable for portable, between-brushing use to enhance oral hygiene
Technology readiness level
Currently at Technology Readiness Level (TRL) 3, VSC BLOCK™ has undergone initial research and development stages, including biochemical and mechanistic validation of MGL inhibition. The next steps involve confirming enzyme inhibition, conducting safety screenings, and testing formulations in short human pilot studies to assess efficacy and scalability. The technology shows promise for future commercial applications in oral care products.
About Sarvotham Care Ltd
Sarvotham Care Limited is an established Contract Development and Manufacturing Organization (CDMO) and Contract Manufacturing Organization (CMO) that provides comprehensive end-to-end solutions for the healthcare, personal care, and home care industries. The company manages the full product lifecycle, including formulation research and development, clinical and pre-clinical services, and commercial-scale manufacturing. Its manufacturing capabilities span various dosage forms, such as granules, powders, tablets, capsules, liquids, creams, and gels. Sarvotham emphasizes technology-driven processes, regulatory compliance, and international quality standards, supported by internal laboratories equipped for advanced microbiological and chemical analysis.
The company serves as a strategic partner to multinational corporations and large Indian firms, focusing on on-time delivery and consistent quality. By offering private label services, Sarvotham enables clients to develop and market their own branded products while leveraging the company's manufacturing expertise and R&D infrastructure. Committed to sustainability and professional integrity, Sarvotham integrates environment, health, and safety (EHS) protocols into its operations, striving to meet both local and global market demands through scalable and innovative manufacturing solutions.
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