Wearable EM field technology for neuropathic pain relief

Overview

CytoEM Innovations presents a groundbreaking technology aimed at alleviating neuropathic pain through a non-invasive, wearable patch that delivers electromagnetic (EM) fields. By specifically targeting the neuronal cytoskeleton, this solution modulates microtubules and actin filaments, which are crucial for signal conduction and modulation, thereby reducing abnormal neuronal excitability associated with pain. This approach promises a drug-free, side-effect-free method to manage pain, adaptable to individual needs and suitable for over-the-counter (OTC) consumer use.

Technical specifications

The technology focuses on using low-frequency EM fields to alter the electrical oscillations generated by microtubules and actin filaments within neurons. The wearable patch is designed for localized application, ensuring targeted treatment of affected areas. Key technical activities include:

• Preclinical Testing: In vitro experiments on cultured dorsal root ganglion (DRG) neurons to determine EM field modulation thresholds.
• Prototype Development: Creation of a safe, localized EM field-emitting patch for consumer use.
• Animal Model Validation: Testing on a murine model of neuropathic pain to assess efficacy and safety.

Technology readiness level

Currently at TRL 3, this technology is in the experimental proof-of-concept stage. Preclinical testing and prototype development are underway, with plans for further validation using cultured neurons and animal models to ensure safety, efficacy, and consumer readiness.