Xnanodex™ no-activating oral care system
XnanodeX™ uses nano-emulsion technology to deliver arginine-based Nitric Oxide deep into the oral biome, enhancing bioavailability and activating pathways for improved circulation and cellular resilience. It powers a comprehensive oral care system, including mouthwash, dental floss, and tooth gel.
Overview
XnanodeX™ is a revolutionary oral care platform that employs advanced nano-emulsion technology to activate endogenous Nitric Oxide (NO) production. Utilizing lipid nanoparticles that are 1,000 times smaller than conventional formats, XnanodeX™ penetrates mucosal tissue instantly. This triggers NO pathways which support improved circulation, cellular resilience, and a balanced oral microbiome. The system comprises a daily NO-activating mouthwash, a dental floss delivering interproximal support, and a tooth gel that remineralizes enamel while sustaining NO production at the gum line. XnanodeX™ offers unmatched bioavailability and long-term efficacy, confirmed over more than four years of real-world use.
Technical specifications
- Nano-emulsion delivery: Arginine-based Nitric Oxide is encapsulated in lipid nanoparticles, allowing deep penetration into the oral biome.
- Sustained NO production: A single treatment maintains NO levels for over 72 hours, far exceeding the typical 6-hour effect of conventional products.
- Comprehensive care system: Includes NO-activating mouthwash, dental floss, and tooth gel, each addressing specific oral health needs with targeted NO delivery.
- Microbial-metabolic modulation: Restores bacterial-enzymatic pathways essential for natural NO synthesis, enhancing circulatory and cellular health.
Technology readiness level
The XnanodeX™ platform is currently at a Technology Readiness Level (TRL) of 3. It is in the early stages of development, with ongoing feasibility studies, formulation compatibility checks, and initial regulatory pathway mapping. Future plans include clinical trials and global regulatory submissions to further validate and scale the technology.
About LifeActiveBio
LifeActive Bio is a pre-clinical biomaterials company that specializes in advanced molecular delivery technology. The company has developed a proprietary, patent-pending system known as the Molecular Administration Platform, which utilizes a natural lipo-surfactant microemulsion to encapsulate molecules for direct absorption through the skin. This technology is designed to bypass traditional first-pass metabolism and eliminate the need for invasive administration methods. Beyond its therapeutic applications, the company also offers the XnanodeX Clean Label Base, a formulation platform specifically engineered for the cosmetics and personal care industries, enabling brands to develop products with streamlined, clean-label ingredient profiles.
The company's technology aims to improve the delivery and bioavailability of both existing and new therapeutic compounds, with potential applications spanning cardiovascular, metabolic, and respiratory health, as well as mental wellness and oncology. By enabling more efficient nutrient and drug absorption without needles or invasive devices, LifeActive Bio seeks to extend human quality of life and enhance therapeutic outcomes. The company operates as a scalable platform, providing white-labeling and licensing opportunities that allow brand and manufacturing partners to integrate its proprietary emulsion technology into their product lines, significantly reducing the time required to move from concept to market-ready samples.
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