Efstratios Stratikos's profile

Efstratios Stratikos

Principal Investigator

University of Athens

I'm working on

7 months ago

Biochemistry of the himmune system

About

Dissects and modulates antigen processing to tune cellular immunopeptidomes. Combines structural biology, biochemistry, and LC-MS proteomics with structure-guided medicinal chemistry to develop selective small-molecule modulators for immuno-oncology and autoimmunity.

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University of Athens

Small molecule inhibitors enhancing tumor immunogenicity by modulating antigen processing

Developed small molecule inhibitors of ERAP1 to reprogram antigen processing in cancer cells, enhancing their immunogenicity. This approach potentially complements immunotherapies like CAR T-cells by broadening antigenic...

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Efstratios Stratikos

Principal Investigator

University of Athens

Work experience

University of Athens

Principal Investigator

Harvard University

Postdoctoral Scientist

1999 - 2004

University of Illinois, Urbana-Champaign

PhD, Biochemistry

1994 - 2004

Top industry applications

Immunology & immune-mediated diseaseOncology & cancer therapeutics

Expertise

BiochemistryImmunologyMedicinal ChemistryProteomicsStructural Biology

Last updated Feb 2026