Jonathan Sanchez's profile

Jonathan Sanchez

Postdoctoral Scientist

Regenerix

I'm working on

7 months ago

Targeting Necroptosis for Neurodegenerative Disease Therapy

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Necroptosis, a form of programmed cell death, is activated in human Alzheimer's disease (AD) brains and animal models of AD. To ameliorate the effects of neuronal death, we propose to develop necroptosis protein-protein interaction inhibitors to reduce off target effects of typical kinase inhibitors

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Regenerix

Small molecule inhibitor of RIPK3-MLKL protein-protein interaction for necroptosis-associated neurodegeneration

A novel small molecule that inhibits the RIPK3-MLKL protein-protein interaction, blocking necroptosis—a regulated neuroinflammatory cell death pathway implicated in Alzheimer's, Parkinson's, ALS, and multiple sclerosis. ...

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Jonathan Sanchez

Postdoctoral Scientist

Regenerix

Work experience

New York University

Postdoctoral Scientist

2022 - Present

Regenerix

Postdoctoral Scientist

2019 - Present

University of Arizona