Juan josé Lasarte's profile

Juan josé Lasarte

Principal Investigator

University of Navarra

I'm working on

7 months ago

Cancer immunotherapy, cell engineering, tumor microenvironment

About

My work focuses on cancer immunotherapy: engineering CAR-T cells, modulating T-cell regulation and innate signals, and reprogramming the tumor microenvironment. We deploy peptide and nanoparticle delivery and checkpoint combinations, translating viral immunology into therapies.

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University of Navarra

Enhancing BCMA CAR t-cell efficacy through glutamine transporter ASCT2 overexpression

A novel approach to improve BCMA CAR T-cell therapy by engineering cells to overexpress the glutamine transporter ASCT2, enhancing their metabolic fitness and antitumor efficacy in glutamine-deprived environments common ...

TechnologyIn developmentUniversity

Juan josé Lasarte

Principal Investigator

University of Navarra

Work experience

University of Navarra

Principal Investigator

1995 - Present

Top industry applications

Immunology & immune-mediated diseaseOncology & cancer therapeuticsPharmaceuticals and drug delivery

Expertise

Cell TherapyGene TherapyImmunotherapy

Last updated Feb 2026