High-throughput E. coli and pichia protein variant screening workflow
Tiered high-throughput workflow for recombinant protein variant expression and screening in E. coli and Komagataella phaffii (Pichia pastoris). Combines 96-well expression, magnetic bead affinity capture, and flow cytome...
Animal-free fermentation platform for precision collagen-supporting peptide ingredients
Defined Bioscience is developing an animal-free fermentation platform for precision collagen-supporting peptides. The process combines designed recombinant collagen-like precursors, engineered proline hydroxylation, cont...
Animal-free precision collagen peptides via fermentation and hydrolysis
An animal-free platform that produces precision collagen-supporting peptides via recombinant collagen-like precursor proteins, microbial fermentation or cell-free expression, controlled enzymatic hydrolysis, and fraction...
Scalable fractionation of egg proteins into functional ingredients
A scalable process platform that fractionates egg-derived feedstocks into compositionally distinct protein and peptide ingredients with application-relevant functional properties, using food-compatible unit operations an...
Computationally guided cell-free protein variant screening platform
An integrated design-build-test platform that pairs computational variant prioritization with automated cell-free expression and screening. It accelerates protein engineering by focusing experiments on high-value variant...
Automated 96-well protein purification-to-screening platform
A modular 96-well automated platform that streamlines recombinant protein purification and prepares assay-ready samples for downstream screening. Using liquid handling automation with magnetic affinity resin, the system ...
Formulated media for enhanced shelf stability in cultivated meat
Defined Bioscience proposes a novel cell culture medium formulation to enhance the shelf stability of cultivated meat by boosting antioxidant content, altering lipid composition, and increasing antimicrobial peptide expr...
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