Machine Learning Guided Transcriptional Biology in Arabidopsis and Catharanthus roseus to unlock Hairy Root Culture as viable scalable solution to metabolite production
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Using an ML model developed in my PIs lab, I'm aiming to understand the complex patterns of transcription factor binding sites (TFBSs) associated with tissue specific gene expression. Most of my work is in model organism Arabidopsis but some preliminary work in the medicinal plant Catharanthus roseus is currently underway. Identifying key tissue specific transcription factor to TFBS interactions may yield possible biosynthetic solutions for increasing availability of pharmaceutically relevant metabolites in scalable hairy root tissue culture.
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