The lateral flow assay is a rapid diagnostic tool that is utilized to detect a wide variety of analytes in simple and complex matrices. These tests are preferred for their ease of use, low cost and quick time to result. As diagnostic technology advances, the consumer expectations for lateral flow assay performance also increases. Increased sensitivity, function in complex matrices, faster time to result and improved accuracy are just a few features where lateral flow tests are challenged to adapt.
Antibodies are the major contributor to lateral flow assay performance. Sensitivity and specificity are two aspects that are predominantly determined by the antibodies used in a test. As such, the generation of high quality antibodies is a critical aspect for immunodiagnostic assay method developers.
What we're looking for
We are looking for collaborators with expertise in developing highly sensitive, specific and robust antibodies for use in lateral flow assays. We are also looking for opportunities to buy or license antibodies that are already developed.
Solutions of interest include:
Connecting with experts: We are looking to connect with experts in developing antibodies for lateral flow assays.
Sponsored research: We are seeking to fund research related to antibodies for lateral flow assays.
Buying/licensing antibodies: We seek to buy or license antibodies that are already developed.
Our must-have requirements are:
Lateral flow functioning antibodies that detect food allergens in food matrices or mycotoxins in grain-based matrices.
Detection is at or below 1 mg/kg allergenic protein or 1 ng/kg for natural toxins.
Our nice-to-have's are:
Ability to acquire the Intellectual property rights of developed antibodies
Once successful, the supply of antibody will cost less than $100/mg.
What's out of scope:
Antibodies that do not function in lateral flow format.
Funding is dependent on the proposal and can be up to $100,000 for a 6-9 month project. Depending on the success of the initial project, follow-up funding could occur.
Gift/award
In most cases, sponsored research is preferred. In the case of gift, funding will be dependent on the proposal and can be up to $100,000 for a 6-12 month project. Depending on the success of the initial project, follow-up funding could occur.
Expertise
Available experts in food safety, diagnostic assays, protein chemistry, protein purification and antibody development.
Tools and Technologies
Access to liquid chromatography equipment use for protein purification and characterization.
Access to ELISA and lateral flow test formats.
Facilities and Services
Partners can send antibodies for purification and characterization. Partners can also utilize our expertise in design and preparation of immunogens and capture reagents.
Q&A with the company
The Q&A is now closed.
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Q.
What target antigens are you looking for? We have antibodies against a list of the target antigens.
We have a technology to develop antibody mimetics for diagnostic applications. We can address multiple allergens (like Ara H1 for example). Would this be responsive to the RFP? I'm happy to discuss more. Chris
Hello Dr. Mazo. We arent at liberty to share our specific epitopes in a public forum, but we can share that we are looking for detection of allergens and toxins such as peanut (AraH1 as an example) and toxins (Aflatoxin as an example).
Thanks for your question and interest!
Jesse
Team Member, Reviewer, Private Company
September 29, 2023
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Q.
Fusion antibodies specialise in the discovery, development and optimisation of antibodies of all formats and frameworks, are you interested in discussing further how we can help? chris.king@fusionantibodies.com
We do have commercial products based on lateral flow assays for the clinical industry. We develop our own monoclonal antibodies. We do not have products for allergens or toxins. Would you be interested in discussing more? rajan@nanospeed.ca