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Free in vivo testing: Unleash your molecule's potential as a crop protector
  • Background
  • What we're looking for
  • What we can offer you
  • Who we are
  • Q&A
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Get them answered by the team at BASF.
Background

You’ve already done all the hard work of synthesizing your molecule. Maybe it wasn’t the blockbuster pharmaceutical you envisioned, but it still has potential!  

 

Now, we would like to partner to bring new life and impact from your chemistry. You may submit multiple compounds, and we will screen them using our computer models. If they are selected, you will receive the biological results for each compound as a potential herbicide, fungicide and insecticide, and you are free to publish the results. 

 

If there is a hit, it’s up to you to decide about follow up collaboration.  

 

Start the collaboration with us: let’s discover together if that next crop protection blockbuster is sitting in your deep freezer! 

 

Process 
  1. Submit proposal on Halo 

  2. Sign MTA agreement through DocuSign 

  3. Upload file with structures to BASF's platform 

  4. In silico evaluation & BASF decision 

  5. In vivo test of selected compound at BASF 

  6. Return of in vivo results for publication 

  7. Further collaboration

What we're looking for

We are looking for novel compounds, such as organic molecules, natural products, and fragment-like molecules, which could be subjected to screening within our research facility, with the goal of developing new crop protection products.

Solutions of interest include:
  • Single chemical compounds (in a dry form)
  • Small organic molecules
  • Natural products
  • Virtual compounds (if deliverable as physical sample by partner after positive in silico testing by BASF)
Our must-have requirements are:
  • The minimum amount of compound we will accept is 5 mg (the standard amount is 8 mg).
  • The material shall have purity greater than 80% as determined by current state-of-the-art analysis.
Our nice-to-have's are:
  • Additional amounts of compound available for further screenings (20-100 mg) if needed.
  • Analogues compounds of submitted molecule if the parent compound turns out to be a hit in the initial screening.
What's out of scope:
  • Extracts or mixtures of compounds
  • Solutions in solvents
  • Metal-containing molecules
  • Polymers
  • Nanoparticles
  • Microorganisms
  • Toxic or explosive compounds
What we can offer you
Benefits:
Data
Biological results from the preliminary tests and results from philanthropic public health programs against human pathogens (e.g. malaria)-if selected by BASF and priori agreed with partner to test.
Expertise
Partner receive logistic support and guidance over each step of the collaboration. Possibility to develop further collaboration with BASF researchers, based on preliminary results.
Facilities and Services
Free shipping of participant´s compounds to BASF. To ensure the best solution and simple procedures, we also provide you free of charge our packaging materials (vials/tubes and boxes).
Compounds and Reagents
Synthesis cost for the re-ordered compound for further in vivo tests could be reimbursed.
Who we are

As a global chemical company, we operate in diverse markets with varying requirements. To ensure responsible conduct and maintain our license to operate, we are guided by our core values and standards. These values shape our daily actions and foster respectful relationships with colleagues, customers, and partners.

Our teams are committed to putting health and safety first, making sustainability a part of every decision, and meeting strict compliance and environmental standards. We embrace diversity—in people, perspectives, and experiences—and promote open feedback grounded in honesty, respect, and trust. We see setbacks as opportunities to learn and improve.

 Learn more
Reviewers
Q&A with BASF

The Q&A is now closed.

Sort by:
Q.
Are there similar schemes for testing proteins?
1
A.
Dear Michelle, Proteins are not in scope of this project. We are interested only in small organic molecules which could be an entry point for our crop protection discovery screening. Please contact me directly if you are interested in other sort of collaboration , E-mail: oipAgro@basf.com best wishes, Anna
AP
Anna aleksandra Michrowska Pianowska, Leader of the Open Innovation Platform Agro and External Synthesis & Compound Acquisition, BASF
November 23, 2023
Is this response helpful?
0
0
Q.
Can our team have a look at the MTA before we decide to participate? Thanks! Brad
BR
Brad Roth, Tech Transfer, University of Nebraska, Lincoln
December 7, 2023
1
A.
Dear Brad, yes, of course. Please check the FAQ under "What are the conditions of MTA?". bets wishes, Anna
AP
Anna aleksandra Michrowska Pianowska, Leader of the Open Innovation Platform Agro and External Synthesis & Compound Acquisition, BASF
December 7, 2023
Is this response helpful?
0
0
A.
Thanks, sorry I missed the FAQ.
BR
Brad Roth, Tech Transfer, University of Nebraska, Lincoln
December 7, 2023
1
Q.
We have an in-house library of about 2K compounds. How many you can screen, even virtually? In which format should they be submitted? CSV? SDF?
1
A.
Dear Gianluca, we can screen your whole library, that is not a problem. First step is an in silico screening, afterwards only selected compounds will be sent to in vivo tests. Considering the format: we prefer either ‘structure data’ file (.sdf) or a ‘comma-separated values’ file (.csv). best wishes, Anna
AP
Anna aleksandra Michrowska Pianowska, Leader of the Open Innovation Platform Agro and External Synthesis & Compound Acquisition, BASF
November 28, 2023
Is this response helpful?
1
0
Q.
Hi, I want to know at what point do we have to get our compounds ready for sending off? I am guessing it will be based on proposal selection.
1
A.
Dear Saadia, After signing of the MTA we ask you to provide us first with a file containing compound structures. We proceed with in silico screening and communicate the outcome to you. Only afterwards we would request physical samples of selected compounds. You also receive from us guideline how to proceed with the shipment and proper packing materials. I hope to work with you soon:)
AP
Anna aleksandra Michrowska Pianowska, Leader of the Open Innovation Platform Agro and External Synthesis & Compound Acquisition, BASF
November 16, 2023
Is this response helpful?
0
0
Q.
Our in vitro studies identified an existing, biodegradable, non-toxic, GRAS-classified material to eliminate major bacterial & fungal agri plant pathogens at low mM concentrations & neutral pH. Of interest?
1
A.
Dear Snezna, Could you please send me some more information about your compounds? Do you have publications? Please write to our E-mail: oipAgro@basf.com Thank you. best wishes, Anna
AP
Anna aleksandra Michrowska Pianowska, Leader of the Open Innovation Platform Agro and External Synthesis & Compound Acquisition, BASF
January 2, 2024
Is this response helpful?
0
0
Q.
Do you accept as bioactive molecules specific oligosaccharides with controled molar mass?
1
A.
Dear Artur, Thank you for the question. Unfortunately, we are not interested in oligosaccharides. best wishes, Anna
AP
Anna aleksandra Michrowska Pianowska, Leader of the Open Innovation Platform Agro and External Synthesis & Compound Acquisition, BASF
January 9, 2024
Is this response helpful?
0
0
Q.
Our materials are in solid form, they do not dissolve in water, they are water stable (hybrid compounds). Could you perform the evaluation tests under these conditions? Thanks.
1
A.
Dear Ioannis, We could perform such screening. Please submit your proposal. Thank you. best wishes, Anna
AP
Anna aleksandra Michrowska Pianowska, Leader of the Open Innovation Platform Agro and External Synthesis & Compound Acquisition, BASF
January 8, 2024
Is this response helpful?
0
0
Q.
Are growth promotion compounds also included?
1
A.
Dear Maggie, No, they are out of scope for this program. best wishes, Anna
AP
Anna aleksandra Michrowska Pianowska, Leader of the Open Innovation Platform Agro and External Synthesis & Compound Acquisition, BASF
January 17, 2024
Is this response helpful?
0
0
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